Two exciting PhD positions are available at the MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, under the supervision of Associate Professor Aurélie Carlier. The first position focuses on the computational modelling of bone regeneration, where the successful candidate will develop advanced in silico models to study bone healing, especially in compromised environments. This project sits at the intersection of mechanistic modelling, data integration, and innovative computational approaches such as Physics-Informed Neural Networks (PINNs). The second PhD position centers on developing an in vitro platform to investigate sex differences in renal drug handling. This interdisciplinary project combines advanced in vitro models with physiologically based pharmacokinetic (PBPK) modelling to unravel sex-specific mechanisms in kidney drug transport, contributing to translational pharmacology and kidney physiology research. Both positions offer the opportunity to join a collaborative, international team at the forefront of regenerative medicine and computational biology. The research environment encourages curiosity, initiative, and interdisciplinary exploration, with a strong emphasis on clinical impact and fundamental scientific questions. Applicants should have a relevant background in computational modelling, biomedical engineering, biology, or related fields. Experience with mechanistic modelling, data integration, in vitro models, or PBPK modelling is highly desirable. For detailed eligibility criteria and funding information, candidates are encouraged to consult the official Maastricht University vacancy pages linked in the announcement. To apply, visit the provided Maastricht University vacancy links for each PhD position and follow the application instructions. Join MERLN Institute to contribute to innovative research in bone regeneration and kidney physiology, and become part of a dynamic academic community in the Netherlands.