This fully funded PhD position at ETH Zürich is part of the ENDOTRAIN MSCA Doctoral Network, focusing on the development of innovative biofluid sampling technologies for localized physiological measurements. The project aims to design and fabricate advanced micromachined platforms, such as microneedles, implantables, and microfluidic systems, enabling minimally invasive and continuous sampling of biofluids like interstitial fluid and muscle tissue. These technologies will facilitate direct analysis of metabolites, hormones, and other biomarkers, with transformative potential for diagnostics and monitoring in sports science, rehabilitation, and muscle-related diseases.

As a doctoral researcher, you will work within Work Package 2 of the ENDOTRAIN network, contributing to the innovation and testing of novel data acquisition and aggregation technologies. Specific research tasks include designing microfabricated systems for precise spatial sampling, investigating methods for minimal tissue disruption and high analyte recovery, quantifying analyte concentrations in dynamic physiological states using mouse models and human subjects, and developing models for local production, metabolism, and diffusion of analytes between blood, interstitial fluid, and tissue.

The position offers interdisciplinary training and collaboration opportunities, including secondments at the University of Bergen (for validation of sampling strategies) and University Hospital Zurich (for human testing). You will be based at ETH Zürich, one of Europe’s leading technical universities, within the Department of Mechanical and Process Engineering and the Department of Health Sciences and Technology. The structured PhD programme includes mandatory participation in ENDOTRAIN network activities such as workshops, retreats, transferable skills courses, and cohort-wide meetings across Europe.

Applicants must hold a Master’s degree in Biomedical Engineering, Physiology, Mechanical Engineering, Materials Science, or a related field, and demonstrate a strong interest in translational health technologies. Excellent English language skills and the ability to collaborate across disciplines are essential. Ideally, candidates will have experience in microfabrication, biocompatible materials, and/or implantable devices. Eligibility requires that candidates have not resided or carried out their main activity in Switzerland for more than 12 months in the 36 months prior to recruitment. Willingness to participate in training activities across Europe is mandatory.

The position is fully funded, offering a competitive salary according to Swiss National Science Foundation regulations, full social security coverage, and a travel and secondment budget. Additional benefits include opportunities for international networking, industry exposure, and career development. Applications are accepted year-round, with a latest start date of August 2026. To apply, submit your application via the ETH Zürich job portal, ensuring you meet all eligibility criteria.