Publisher
source

University of Bristol

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Funded PhD in Cell Competition Mechanisms in Breast Cancer Susceptibility and Early Tumour Initiation University of Bristol in United Kingdom

Degree Level

PhD

Field of study

Biology

Funding

Funded through the GW4 BioMed3 MRC Doctoral Landscape Programme. Funding includes UK tuition fees and a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27, updated annually). Additional research training and support funding of up to £5,000 per annum is available.

Deadline

Oct 21, 2026

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Country

United Kingdom

University

University of Bristol

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Keywords

Biology
Medical Science
Breast Cancer
Genetic Epidemiology
Rna-seq
Bioinformatic

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About this position

Funded PhD opportunity at the University of Bristol in the School of Biochemistry and Biomedical Sciences, within the GW4 BioMed3 MRC DTP.

This project investigates cell competition in breast cancer susceptibility and early tumour initiation, with a strong focus on TP53, BRCA1/2, cancer risk, and tumour-host cell interactions. The research combines genetic epidemiology, bioinformatics, and molecular/cell biology. You will use Mendelian randomization, large breast cancer datasets (including BCAC and CIMBA), TCGA expression data, and laboratory models to validate candidate genes and study mechanisms of action.

Training includes 2D and 3D cell culture, fluorescence confocal microscopy, flow cytometry, immunohistochemistry, RNA sequencing, image analysis, and bioinformatic analysis. The project also includes organoid work using human pluripotent stem cells, primary mammary cells, and patient-derived breast organoids.

Funding: UK tuition fees plus a doctoral stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27), with up to £5,000 per year additional research training/support funding.

Eligibility: Students worldwide may apply. The post does not specify a required degree classification or language waiver in the text provided.

Deadline: Apply online by 5:00pm on Wednesday, 21 October 2026. Shortlisting and interviews follow later, and the studentship starts on 1 October 2027.

Funding details

Funded through the GW4 BioMed3 MRC Doctoral Landscape Programme. Funding includes UK tuition fees and a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27, updated annually). Additional research training and support funding of up to £5,000 per annum is available.

What's required

Applicants should be interested in a PhD-level research project combining genetic epidemiology, bioinformatics, and laboratory-based molecular and cell biology. The project involves Mendelian randomization, analysis of large breast cancer datasets, RNA sequencing, 2D/3D cell culture, microscopy, flow cytometry, immunohistochemistry, and organoid work. The post is open to students worldwide; no specific degree classification, language test, or prior experience is explicitly stated in the post.

How to apply

Check the GW4 BioMed website for the list of projects and application instructions. Select up to two projects and submit one application per candidate. Complete the online application form for an offer of funding by 5:00pm on 21 October 2026, then make a separate application for an offer to study if successful.

More information can be found here

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