PhD in Antibody Reprogramming, Tumour Microenvironment and Immune Resistance University of Bath in United Kingdom

Fully funded PhD opportunity at the University of Leeds in drug discovery technologies , working directly with industry on new approaches using Adhiron reagents . The project sits at the interface of academic research and industry and focuses on developing new technologies for understanding and targeting proteins involved in disease. The successful candidate will work with techniques including protein engineering , phage display , and structural biology , with the aim of creating new reagents an...

Postdoctoral Research Scientist in Brain Tumour Research at the Ludwig Institute for Cancer Research, University of Oxford (Headington, Oxford, UK). This postdoctoral opening is in the Pathania Laboratory with Dr Manav Pathania and focuses on brain tumour biology, especially ependymoma and atypical teratoid/rhabdoid tumours . The project aims to develop disease-representative models and use them to identify precision therapy opportunities, tumour-microenvironment interactions, and mechanisms of ...

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences on beta-lactam antibiotic targets for improving melioidosis treatment. The project focuses on the soil-borne pathogen Burkholderia pseudomallei , a major cause of melioidosis, and aims to understand how clinically important beta-lactams interact with bacterial cell-wall enzymes such as penicillin-binding proteins (PBPs) and L,D transpeptidases (LDTs) . The work combines recombinant protein expre...

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences with Dr Maisem Laabei on targeted covalent macrocycles for immune-mediated diseases . The project focuses on the complement system and pathway-specific inhibition of key serine proteases, especially C1s and factor D , to develop more selective therapies for inflammatory and autoimmune conditions. Research themes include biochemistry , molecular biology , microbiology , phage display , chemical s...

PhD opportunity at the University of Bath in the GW4 BioMed3 MRC Doctoral Landscape Programme (DLP): Designing Cell-Accumulating Covalent Inhibitors to Combat Gram-Negative Antimicrobial Resistance . This project sits at the interface of medicinal chemistry, microbiology, chemical biology, biochemistry, and pharmaceutical chemistry . The research aims to understand how to design covalent inhibitors that can accumulate inside Gram-negative bacteria, overcome permeability and efflux barriers, and ...