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University of Melbourne

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PhD in Epigenomic and Transcriptional Control of EZH-Mediated Human Islet Organoid Regeneration University of Melbourne in Australia

Degree Level

PhD

Field of study

Biomedical Engineering

Funding

Applicants are automatically considered for a range of scholarships, but some scholarships require a standalone application. No stipend amount, tuition coverage, or funding guarantee is specified in the post.

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Country

Australia

University

University of Melbourne

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Keywords

Biomedical Engineering
Biology
Medical Science
Transcriptional Profiling
Epigenetic
Insulin

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About this position

PhD opportunity at the University of Melbourne in Epigenomic and Transcriptional Control of EZH-Mediated Human Islet Organoid Regeneration.

This research degree project investigates how inhibition of EZH histone methyltransferases can reprogram adult human pancreatic cells toward endocrine identity. The PhD candidate will work with human pancreatic ductal cells and organoid systems, combining transcriptomic profiling and epigenomic profiling to study chromatin remodelling, endocrine lineage activation, and re-expression of key beta-cell/endocrine genes such as NGN3, PDX1, MAFA, and INS.

The project is offered by the Baker Department of Cardiometabolic Health, Faculty of Medicine, Dentistry and Health Sciences, with supervision from Prof Sam El-Osta and external co-supervisors Dr Caroline Frørup and Ms. Safiya Naina Marikar.

This is a PhD opening. Applicants are automatically considered for a range of scholarships, although some scholarships may require a separate application. No specific stipend amount or tuition details are listed in the post.

The opportunity is based at the Baker Heart and Diabetes Institute in Australia. The page does not list a deadline, so interested candidates should submit an Expression of Interest as soon as possible and review the full project page for scholarship and application instructions.

Funding details

Applicants are automatically considered for a range of scholarships, but some scholarships require a standalone application. No stipend amount, tuition coverage, or funding guarantee is specified in the post.

What's required

Applicants should be eligible for a Doctor of Philosophy (PhD) and have strong interest in epigenomics, transcriptional profiling, chromatin biology, pancreatic biology, organoid models, and endocrine cell differentiation. The post highlights work with human pancreatic ductal cells and organoids; prior experience in molecular biology, transcriptomics, epigenomics, or bioinformatics would be relevant, though no explicit GPA or language requirements are stated.

How to apply

Submit an Expression of Interest through the project page. Review the full project details and scholarship information before applying. If a separate scholarship application is needed, follow the linked instructions on the opportunity page.

More information can be found here

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