Publisher
source

Cardiff University

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PhD in Huntington's Disease: DNA Damage, PARP Signalling, Mitochondrial Failure and Metabolic Collapse Cardiff University in United Kingdom

Degree Level

PhD

Field of study

Chemistry

Funding

Funded PhD studentship through the GW4 BioMed3 MRC Doctoral Landscape Programme. Covers UK tuition fees and a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27, updated annually). Additional research training and support funding of up to £5,000 per annum is available. Open to UK and international applicants.

Deadline

Oct 21, 2026

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Country

United Kingdom

University

Cardiff University

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Keywords

Chemistry
Biology
Neuropsychology
Sequencing Technology
Drosophila Research
Medical Science
Dna Damage
Huntington's Disease
Metabolomic

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About this position

PhD opportunity at Cardiff University in the Cardiff School of Medicine on Huntington's disease, with a focus on why vulnerable neurons die.

This project investigates the links between DNA damage, PARP signalling, mitochondrial failure, and metabolic collapse in neurodegeneration. The student will use a multidisciplinary toolkit including Drosophila genetics, human stem cell-derived neurons, DNA damage assays, sequencing approaches, live-cell imaging, and metabolomics.

The project is based at Cardiff University and connected to the collaborative GW4 and UK Dementia Research Institute research communities, offering multidisciplinary training in disease mechanisms and therapeutic strategy testing.

Funding: This is a funded PhD studentship through the GW4 BioMed3 MRC Doctoral Landscape Programme. It includes UK tuition fees, a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27), and up to £5,000 per annum in additional research training and support funding. UK and international applicants may apply.

Eligibility: Applicants should have, or be about to obtain, a first or upper second-class UK honours degree or an equivalent qualification. English language requirement: IELTS 6.5 overall with 5.5 in all subskills, or an acceptable alternative.

Application: Review the project list and instructions on the GW4 BioMed website, choose up to two projects, and submit one application per candidate. If shortlisted, you will later need to apply for an offer to study at the chosen institution.

Deadline: The listing shows Wednesday, 21 October 2026.

Funding details

Funded PhD studentship through the GW4 BioMed3 MRC Doctoral Landscape Programme. Covers UK tuition fees and a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27, updated annually). Additional research training and support funding of up to £5,000 per annum is available. Open to UK and international applicants.

What's required

Applicants must have obtained, or be about to obtain, a first or upper second-class UK honours degree, or an equivalent qualification gained outside the UK. English language requirement is IELTS 6.5 overall with 5.5 in all subskills, or an acceptable alternative.

How to apply

Review the project list and application instructions on the GW4 BioMed website. Select up to two projects and submit one application per candidate. If shortlisted, you will later need to apply for an offer to study at the chosen institution.

More information can be found here

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