PhD in Microbial Metabolites, Lipid Immunometabolism and T-Cell Function at Luxembourg Institute of Health Luxembourg Institute of Health in

Call for applications for a PhD student position in the UNLIMITED Maria Skłodowska-Curie Doctoral Network at the Luxembourg Institute of Health in Esch-sur-Alzette, Luxembourg.

The project, DC14: Microbial Metabolites as Immune Metabolic Switches, focuses on how microbial metabolites and lipid metabolism regulate T-cell function and immune responses. The research sits at the intersection of immunology, biochemistry, microbiome research, lipidomics, and single-cell metabolic analysis.

Research topics include screening microbial and tissue metabolites affecting T-cell function, studying lipid remodeling in effector T cells, and using advanced methods such as lipidomics, SCENITH, Met-Flow, CRISPR/Cas9, flow cytometry-based metabolic mapping, and immunometabolic functional assays. The project also includes secondments with partner labs in Germany, including the University Medical Center Mainz and ActiTrexx Lab.

Eligibility highlights: applicants should have or be finishing a Master’s degree in Immunology, Molecular Biology, Biochemistry, Biomedical Sciences, or a related life-science field. MSCA mobility rules apply: applicants must not already hold a PhD and must not have lived or worked in Luxembourg for more than 12 months in the last 3 years.

Funding and duration: this is a 36-month full-time PhD contract with an MSCA-funded salary package, plus doctoral training, transferable skills training, and international research visits.

How to apply: submit the application as a single PDF in English via the LIH recruitment portal only. Include a CV (max 2 pages plus publications if any), cover letter (max 1 page), BSc and MSc transcripts, at least two reference letters and referees, and optional certificates. Incomplete applications and email submissions will not be considered.

Reference: MC/PhDUN/DB/0626.