Publisher
source

University College Dublin

PhD in Model-Supported Design of Scalable Cost-Effective Tangential Flow Filtration (TFF) Purification for Viral Vector Biomanufacture University College Dublin in Ireland

Degree Level

PhD

Field of study

Biomedical Engineering

Funding

Funded PhD position with a stipend of €25,000 per annum plus fees for 4 years.

Deadline

Expired

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Country

Ireland

University

University College Dublin

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Keywords

Biomedical Engineering
Chemical Engineering
Materials Science
Biology
Gene Therapy
Medical Science
Biochemical Engineering
Biomanufacturing

About this position

PhD opportunity at University College Dublin in the School of Chemical & Bioprocess Engineering with Dr Jessica Whelan.

This funded project focuses on the model-supported design of scalable, cost-effective tangential flow filtration (TFF) for the purification of viral vectors, especially AAV used in in vivo gene therapy. The research aims to develop a robust framework for clarifying and concentrating post-production reactor lysate before chromatography, improving downstream yield, process sustainability, and manufacturing economics.

Key research themes include chemical engineering, bioprocess engineering, biotechnology, systems engineering, membrane fouling, product recovery and stability, and optimization of complex process parameters. The project is designed to support large-scale commercial manufacturing of viral vectors.

Funding includes a stipend of €25,000 per year plus fees for 4 years. The opportunity is open to qualified applicants of any nationality.

Eligibility highlights: a relevant scientific or engineering degree is required (for example chemical/biochemical engineering or biotechnology), along with a strong academic record, motivation, curiosity, enthusiasm, and the ability to work independently and in a team.

To apply, complete the application form and the Rinn Centre Expression of Interest form by 15 August 2026. The EoI must be completed in a single session.

Funding details

Funded PhD position with a stipend of €25,000 per annum plus fees for 4 years.

What's required

Applicants should hold or be soon to hold a primary degree in a relevant scientific or engineering discipline such as chemical engineering, biochemical engineering, biotechnology, or a related field. Candidates should have an excellent academic record and be motivated, curious, enthusiastic, able to work independently and as part of a team. Applications are welcome from qualified applicants of any nationality.

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