Publisher
source

University Medical Center Utrecht, Utrecht University

PhD in Tertiary Lymphoid Structures in Disease University Medical Center Utrecht in Netherlands

Degree Level

PhD

Field of study

Immunology

Funding

4-year PhD position with a maximum salary of €3,217 gross per month based on full-time employment (36 hours/week). Additional benefits include an annual benefit of 8.3%, holiday allowance, travel expenses, and career opportunities.

Deadline

Sep 1, 2026

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Country

Netherlands

University

University Medical Center Utrecht, Utrecht University

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Keywords

Immunology
Biology
Lung Cancer
Neuropsychology
Medical Science
Nanomedicine
Rna-seq
Cell Culture Techniques
Lipid Nanoparticles
Lung Transplantation
Transcriptomic
Biomedicine

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About this position

University Medical Center Utrecht is advertising a 4-year PhD position on tertiary lymphoid structures (TLS) in disease. The project examines how TLS shape local immune responses across multiple contexts, including inborn errors of immunity (APDS), lung cancer, and lung transplantation, with the goal of identifying new therapeutic targets.

You will work in the laboratory of Dr. Theo van den Broek at the Center for Translational Immunology (CTI), UMC Utrecht, and collaborate with researchers at Erasmus MC and the Wilhelmina Children’s Hospital. The project bridges experimental models and human immunology, including murine meninges studies, tonsillar samples from APDS patients, and comparative analyses of TLS organization and immune composition in different tissues and disease settings.

Research methods include flow cytometry, spectral flow cytometry, advanced imaging, molecular and transcriptomic analyses, laser-capture microdissection, RNA sequencing, and the generation/characterization of lipid nanoparticles. The broader environment is interdisciplinary, spanning immunology, tissue biology, neuroscience, and clinical research.

Applicants should have a background in biomedical sciences. Experience with cell culture, spectral flow cytometry, RNA sequencing, and large dataset analysis is preferred. Affinity with immunology, plus strong communication, organization, flexibility, adaptability, and teamwork skills, are highlighted.

The position is based in Utrecht, Netherlands. Salary is up to €3,217 gross per month for a full-time 36-hour week, plus an annual benefit of 8.3%, holiday allowance, travel expenses, and career opportunities. The deadline is 1 September 2026.

Funding details

4-year PhD position with a maximum salary of €3,217 gross per month based on full-time employment (36 hours/week). Additional benefits include an annual benefit of 8.3%, holiday allowance, travel expenses, and career opportunities.

What's required

Background in biomedical sciences is required. The ideal candidate has outstanding experimental abilities and preferably experience with cell culture, spectral flow cytometry, RNA sequencing, and analysis of large datasets. Affinity with immunology is desirable. Strong communication, organizational skills, flexibility, adaptability, and teamwork are expected.

How to apply

Apply via the AcademicTransfer application page using the Apply now button. For questions, contact Theo van den Broek by email.

More information can be found here

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