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Instituto de Productos Naturales y Agrobiología (IPNA-CSIC)

PhD Position in Bioorthogonal and Supramolecular Chemistry Instituto de Productos Naturales y Agrobiología in Spain

Degree Level

PhD

Field of study

Biochemistry

Funding

Available

Deadline

Oct 31, 2026

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Country

Spain

University

Instituto de Productos Naturales y Agrobiología (IPNA-CSIC)

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Keywords

Biochemistry
Chemistry
Organic Chemistry
Biology
Chemical Biology
Supramolecular Chemistry
Kinetic

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About this position

A fully funded 48-month PhD position is available at the Instituto de Productos Naturales y Agrobiología (IPNA-CSIC) in La Laguna, Canary Islands, Spain, within the Molecular Sciences department.

The project sits at the interface of organic chemistry, biochemistry, and supramolecular chemistry. The successful candidate will work on controlling bioorthogonal reactions through mechanical bonding using rotaxanes. The research involves synthesizing interlocked molecules and their non-interlocked analogues, studying the kinetics of bioorthogonal reactions, and evaluating how the macrocycle around the axle influences reactivity. The work will also explore systems that respond to specific biological environments and test the control of bioorthogonal reactions in cells, with possible final applications in controlled drug release and sensing.

This PhD is especially relevant for students interested in supramolecular design, chemical biology, molecular recognition, reaction kinetics, and functional interlocked architectures. Selected recent references provided in the advert highlight the group’s work on rotaxane-controlled tetrazine reactivity, dynamic libraries, and fluorescent supramolecular sensing.

Funding is fully provided for the 48-month duration. The package includes a net salary of 1825 EUR per month after taxes, plus additional funding for short stays or administrative costs. The position is full-time (35 hours per week) and starts tentatively on 1 February 2027, with some flexibility.

Eligibility requires an MSc in Chemistry or a closely related discipline from an educational system within the European Higher Education Area (EHEA). Prior experience in supramolecular chemistry, bioorthogonal chemistry, or biomedicinal chemistry is strongly advantageous, and excellent English is required.

Applications should be sent by email before 31 October 2026 or until the position is filled. Applicants must submit a CV including at least two referees, academic transcripts, and a motivation letter to [email protected], using the subject line “PhD position 2026”.

Funding details

Available

What's required

Candidates must hold an MSc in Chemistry or a closely related discipline obtained under educational systems belonging to the European Higher Education Area (EHEA). Experience in supramolecular chemistry, bioorthogonal chemistry and/or biomedicinal chemistry will be highly considered. Good knowledge of English is required.

How to apply

Send a CV including at least two references, academic transcripts, and a motivation letter by email to [email protected]. Use the subject line 'PhD position 2026'. Apply before the position is closed or once a selected candidate is found.

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