Publisher
source

Stockholm University

PhD positions in Biophysics: Cryo-EM Structural Biology and AI-Driven Computational Modeling of Membrane Proteins Stockholm University in Sweden

Degree Level

PhD

Field of study

Computer Science

Funding

Fixed-term doctoral employment for up to four years full-time. The position is a salaried PhD employment; it may include up to 20% teaching, research, or administration. No stipend amount is stated.

Deadline

Expired

Country flag

Country

Sweden

University

Stockholm University

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Keywords

Computer Science
Chemistry
Biophysics
Deep Learning
Biology
Structural Biology
Molecular Dynamics
Computational Physics
Cryo-electron Microscopy
Bioinformatic
Membrane Protein
Physics

About this position

Two PhD positions are open in biophysics at Stockholm University / SciLifeLab in Stockholm, Sweden, with a deadline of 22 April 2026. The post highlights two complementary research directions in membrane protein science: cryo-EM structural biology of membrane proteins in native membranes and computational biophysics / AI-driven modeling of membrane proteins.

The experimental PhD project focuses on cryo-EM, structural biology, and membrane protein behavior in native-like environments, including ligand-gated ion channels, liposomes, and cell-derived membrane vesicles. The project emphasizes advanced sample preparation, image classification, and data processing to resolve structures in heterogeneous membrane systems.

The computational PhD project focuses on AI, molecular dynamics, bioinformatics, and simulation-based inference for membrane proteins, especially pentameric ligand-gated ion channels (pLGICs). The work combines cryo-EM data, deep learning, and modeling of conformational transitions, allosteric modulation, and lipid interactions.

Eligibility is based on Stockholm University’s PhD entry requirements. Applicants should have a second-cycle degree or equivalent, plus the required background in Physics or Chemistry and advanced coursework in Biophysics, Biochemistry, or Physical Chemistry. Strong English, analytical ability, collaboration, initiative, and independence are important. For the experimental track, extensive lab experience is expected; for the computational track, strong experience in computational methods is preferred.

The positions are salaried doctoral employments for up to four years full-time, with possible limited duties in teaching, research, or administration. Interested candidates should apply through Stockholm University’s recruitment system and upload a personal letter, CV, and all requested supporting documents before the deadline.

Funding details

Fixed-term doctoral employment for up to four years full-time. The position is a salaried PhD employment; it may include up to 20% teaching, research, or administration. No stipend amount is stated.

What's required

Applicants must meet general PhD entry requirements: a second-cycle degree, or at least 240 higher education credits with 60 credits at second-cycle level, or equivalent knowledge. For the Biophysics program, applicants must have at least 120 credits in Physics or Chemistry and at least 60 credits at second level in Biophysics, Biochemistry or Physical Chemistry, including a 30-credit degree project. The selection emphasizes strong documented knowledge and skills relevant to the thesis project, excellent written and oral English, analytical thinking, collaboration, creativity, initiative, and independence. For the experimental project, extensive laboratory experience is expected and cryo-EM experience is an advantage. For the computational project, a very strong profile in computational work is expected, including bioinformatics, molecular modeling, simulations, or AI.

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Professors

Professor

University Name
Country flag

Sweden

Research Interests

Biochemistry

Pharmacology

Allosteric Regulation

G Protein-coupled Receptor

Molecular Physics