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University of Birmingham

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PhD Studentship in Molecular Drivers of Enhancer Rewiring in Blood Cancers University of Birmingham in United Kingdom

Degree Level

PhD

Field of study

Biology

Funding

Fully funded 3-year PhD studentship funded at UK Home Rates, with a starting UKRI Home Tuition Fee of £5,151 and a starting tax-free stipend of £21,805.

Deadline

Nov 6, 2026

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Country

United Kingdom

University

University of Birmingham

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Keywords

Biology
Medical Science
Transcriptional Regulation
Multiple Myeloma
Epigenetic
Genomic

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About this position

PhD studentship at the University of Birmingham in the Department of Cancer and Genomic Sciences on molecular drivers of enhancer rewiring in blood cancers, with a focus on multiple myeloma, gene regulation, epigenetics, transcription factors, chromatin activation, and genome organisation.

The project investigates how B-lineage transcription factors and chromatin-associated complexes such as Mediator, P300/CBP, and CTCF shape gene regulatory networks in myeloma. The research aims to identify altered regulatory networks and map key TF-coactivator interactions, using cell and primary patient models.

This is a fully funded 3-year PhD studentship for UK Home students. Funding includes a starting UKRI Home Tuition Fee of £5,151 and a starting tax-free stipend of £21,805.

Applicants should have a first-class or upper second-class honours degree, and may also have a Master’s degree or relevant research experience. Preferred backgrounds include biochemistry, molecular biology, genetics, and bioinformatics. Experience with proteomics and/or genomics datasets is highly desirable, along with strong analytical and communication skills.

Supervision is provided by Dr Tianyi Zhang, Professor Guy Pratt, and Professor Sarah Dimeloe, offering training across genome biology, immunology and immunotherapy, cancer biology, biochemistry, molecular biology, proteomics, and genomics (including ChIP-seq, RNA-seq, and ATAC-seq).

To apply, send a CV, two academic referees, and a 1–2 page personal statement to Tianyi Zhang by email. The closing date is 6 November 2026.

Funding details

Fully funded 3-year PhD studentship funded at UK Home Rates, with a starting UKRI Home Tuition Fee of £5,151 and a starting tax-free stipend of £21,805.

What's required

Applicants should have a first-class or upper second-class honours undergraduate degree, a Master’s degree and/or relevant research experience in biochemistry, molecular biology, genetics, or bioinformatics. Skills and proven research experience in proteomics and/or genomics datasets are highly desirable. Strong analytical ability, communication skills, and enthusiasm for collaborative research are essential. UK Home students are eligible.

How to apply

Prepare a CV with two academic referees and a 1–2 page personal statement covering your research interests, experience, skills, and motivation for a PhD. Send the application documents in electronic format to Tianyi Zhang by email.

More information can be found here

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