PhD Studentship in Single-Cell Analysis of Immune-Tumor Microenvironment Interactions INSERM in France

This PhD studentship at the Centre d'Immunologie Marseille Luminy (INSERM) in France provides an outstanding opportunity to explore the intricate interactions between immune cells and the tumor microenvironment using advanced single-cell analysis and spatial proteogenomics. The successful candidate will develop and implement experimental workflows for high-dimensional data acquisition and apply state-of-the-art bioinformatics tools to analyze complex, multidimensional datasets.

The research will leverage sophisticated mouse genetic models of cancer, conditional gene targeting, single-cell RNA sequencing, spectral flow cytometry, multiplex imaging, and spatial genomics to dissect the immunological and molecular profiles of tissues and cells from animal models of cancer. The project aims to generate mechanistic insights in collaboration with computational biologists and to investigate the functional immunological status of cancers and their microenvironments. The student will be responsible for establishing protocols for sample collection and analysis, maintaining accurate records and databases, and contributing to the research initiatives of the team and the Centre.

The position is full-time, based in Marseille, and offers a fixed-term contract of 36 months with the possibility of a 12-month extension. Applicants should hold a Master's degree in biological sciences or a related field, have experience with experimental mouse models in immunology or oncology, and be familiar with single-cell omics technologies.

Good English proficiency is required. The application deadline is December 1, 2025, and the position is expected to start on January 1, 2026. For further details, candidates can visit the lab's academic page or contact Dr. Toby Lawrence directly via email.