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Evelien Adriaenssens

1 week ago

PhD Studentship: Understanding the Microbiome and Phageome in Chronic Lung Infections for the Development of Phage Therapy University of East Anglia in United Kingdom

I am recruiting a PhD student to study the microbiome and phageome in chronic lung infections for phage therapy development at the University of East Anglia.

University of East Anglia

United Kingdom

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Keywords

Microbiology
Virology
Biology
Health Science
Personalized Medicine
Translational Medicine
Bacteriophage Therapy
Bacteria
Microbiome Research
Dna Analysis
Lung Disease
Bacteriophage
Bioinformatic
Respiratory Diseases

Description

[4-year fully-funded studentship including direct payment of tuition fees, annual stipend for living expenses (£20,780 for 2025/26), and a Research Training Support Grant each year.] This PhD studentship at the University of East Anglia focuses on understanding the microbiome and phageome in chronic lung infections, specifically bronchiectasis, to advance the development of phage therapy. Bronchiectasis is a prevalent chronic respiratory disease, and recurrent infections with Pseudomonas aeruginosa significantly worsen patient outcomes. The project aims to deepen knowledge of bacterial and phage communities in bronchiectasis sputum, enabling more informed decisions about personalised phage therapy. The research is primarily computational, involving bioinformatics analyses of the microbiome and phageome, complemented by laboratory work such as DNA extractions and microbial isolations. The studentship is MRC-funded and based at the Quadram Institute Bioscience, in collaboration with the Norfolk and Norwich University Hospital. The successful candidate will join Dr Evelien Adriaenssens’s group, an expert in viromes and microbiome, with support from Prof Eleanor Mishra, a respiratory consultant and associate clinical professor. The Quadram Institute offers a vibrant research environment at the intersection of fundamental and translational research, with extensive training opportunities, scientific support, and funding for conference attendance. The position is fully funded for four years, covering tuition fees, a stipend for living expenses (£20,780 for 2025/26), and a Research Training Support Grant. Applicants should hold at least an Upper Second-Class Honours degree in Microbiology, Biotechnology, Bioinformatics, or a related discipline, and demonstrate expertise in either microbiology, molecular biology, or bioinformatics, with a willingness to learn complementary skills. Advanced bioinformatics skills, including command-line proficiency, are essential. English language requirements are IELTS 6.5 overall, with no less than 6 in each category. The PhD student will be based at the Quadram Institute building on the Norwich Research Park, joining a dynamic research community. The application deadline is 6 January 2025, with the program starting on 1 October 2026. For eligibility and application details, visit the provided university links.

Funding

Available

How to apply

Apply online via the University of East Anglia postgraduate research application portal. Review eligibility and application instructions at http://www.uea.ac.uk/phd/mmbdtp. Prepare required documents including degree transcripts and proof of English proficiency. Contact the university for further details if needed.

Requirements

Applicants must have at least a UK equivalent Bachelors (Honours) degree with a minimum of Upper Second-Class (2:1) in Microbiology, Biotechnology, Bioinformatics, or a related field. Appropriate expertise in either microbiology, molecular biology, or bioinformatics is required, with a willingness to learn about the other aspects. Advanced skills in bioinformatics, including command-line usage, are essential. English language proficiency is required: IELTS 6.5 overall, with no less than 6 in each category.

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