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Nick Polizzi

6 days ago

Postdoc Positions in In Situ Protein Sequencing and Cryptic Pocket Drug Discovery Dana-Farber Cancer Institute in United States

Degree Level

Postdoc

Field of study

Computer Science

Funding

Postdoc positions are funded by the Keck Foundation. Two projects are available: one on in situ protein sequencing and one on modeling cryptic druggable pockets for drug discovery.

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Country

United States

University

Dana-Farber Cancer Institute

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Keywords

Computer Science
Chemistry
Biomedical Engineering
Deep Learning
Biology
Computational Biology
Medical Science

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About this position

Nick Polizzi is recruiting postdoctoral researchers for two new projects at Dana-Farber Cancer Institute / Harvard Medical School, with collaboration from Ed Boyden’s group at MIT and another project involving Scripps and MGH.

The first opening focuses on in situ protein sequencing, including the development of new peptide binders to enable single-molecule protein sequencing. This role is described as a combined computational + experimental position and is funded by the Keck Foundation.

The second opening is a computational postdoc focused on deep-learning models for predicting cryptic druggable pockets in human proteins using proprietary data. The lab notes that there are substantial resources available to train models from scratch and fine-tune existing approaches.

Applicants should email a CV and cover letter. The post says the positions could start as soon as possible. If you have a background in protein modeling, protein design, computational biology, experimental protein science, or drug discovery, this may be a strong fit.

Funding details

Postdoc positions are funded by the Keck Foundation. Two projects are available: one on in situ protein sequencing and one on modeling cryptic druggable pockets for drug discovery.

What's required

Postdoctoral researchers with interest in protein sequencing, peptide binder development, computational modeling, or drug discovery. The protein sequencing project is a combined computational and experimental role; the cryptic pocket project is primarily computational, with some experimental background welcomed. Applicants should send a CV and cover letter; start date can be as soon as possible.

How to apply

Email Nick Polizzi with your CV and cover letter if interested. Mention which project fits your background: protein sequencing or cryptic pocket drug discovery.

More information can be found here

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