Rice University
2 weeks ago
Postdoctoral Associate in Protein Self-Assembly and Structural Biology at Rice University Rice University in United States
Degree Level
Postdoc
Field of study
Chemistry
Funding
Postdoctoral Research Associate position funded by an Advanced Research + Invention Agency-funded S-LATTICE project; subject to contract negotiations. No stipend amount or tuition details are provided.
Deadline
Sep 30, 2026
Country
United States
University
Rice University

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About this position
Postdoctoral Associate in BioSciences at Rice University (Houston, Texas, United States).
Dr. Caroline Ajo-Franklin’s lab is recruiting a postdoctoral research associate for the S-LATTICE project, focused on protein self-assembly, structural biology, biophysics, synthetic biology, and materials science. The project aims to engineer microbial surface layer (S-layer) proteins into macroscopic, defect-free, metal-coordinating 2D frameworks for advanced applications.
The successful candidate will lead efforts to assemble purified S-layer proteins at the air-water interface, optimize crystal formation, express and purify proteins in E. coli, and develop secretion-based production systems in multiple bacterial organisms. The role also includes quantitative lattice characterization, data analysis, communication with collaborators, and contributions to publications, reports, and lab management.
Required: Ph.D. in Biophysics, Biochemistry, Structural Biology, Chemistry, Materials Science, or a closely related field. The post emphasizes experience with Langmuir troughs or interfacial protein assembly, recombinant protein expression/secretion, biochemical analysis, TEM/STEM, ellipsometry, and strong communication and project management skills.
Preferred: Experience with microbial chassis such as E. coli, B. subtilis, and C. crescentus; surface-layer proteins; lipid films; cryo-EM, AFM, GI-WAXS, SAXS; mentoring; and research equipment management.
Funding: The position is part of an Advanced Research + Invention Agency-funded project and is subject to contract negotiations. No stipend amount is listed.
Deadline: 30 Sep 2026.
Apply via the official Rice University candidate portal linked in the post.
Funding details
Postdoctoral Research Associate position funded by an Advanced Research + Invention Agency-funded S-LATTICE project; subject to contract negotiations. No stipend amount or tuition details are provided.
What's required
Ph.D. in Biophysics, Biochemistry, Structural Biology, Chemistry, Materials Science, or a closely related field. Strong experience or familiarity with self-assembly using Langmuir troughs or protein physical chemistry at liquid-air/liquid-solid interfaces, recombinant protein expression and secretion, biochemical analysis, and electron microscopy (TEM/STEM) and ellipsometry. Strong verbal and written communication, ability to publish and present research, collaborative skills, project/time management, data organization, and adherence to lab safety are required. Preferred experience includes microbial chassis such as E. coli, B. subtilis, and C. crescentus, surface-layer proteins, lipid films, cryo-EM, AFM, GI-WAXS, SAXS, mentoring, and equipment management.
How to apply
Use the application link provided in the post to open the Rice University candidate experience portal. Review the job details and submit your application through the portal. Apply before 30 Sep 2026.
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