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Texas A&M University Health Sciences Center

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Postdoctoral Research Associate in Biochemistry and Diagnostic Development at Texas A&M University Texas A&M University Health Science Center in United States

Degree Level

Postdoc

Field of study

Biochemistry

Funding

This is a grant-funded postdoctoral position. Future employment may be contingent upon future funding. Proposed salary is commensurate. Standard Texas A&M employee benefits are listed, including medical, dental, vision, life, disability, paid leave, retirement, and tuition assistance.

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Country

United States

University

Texas A&M University Health Sciences Center

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Keywords

Biochemistry
Molecular Biology
Chemistry
Microbiology
Biomedical Engineering
Biology
Structural Biology
Chemical Biology
Protein Purification
Medical Science

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About this position

Texas A&M University Health Science Center is hiring a Postdoctoral Research Associate in the Department of Microbial Pathogenesis and Immunology at the Cirillo Laboratory in Bryan, Texas, United States.

The project focuses on developing and optimizing Reporter Enzyme Fluorescence (REFtb), a rapid tuberculosis diagnostic platform based on Mycobacterium tuberculosis beta-lactamase BlaC and fluorogenic substrate chemistry. Research activities include protein expression and purification, enzyme kinetics, fluorogenic probe evaluation, reagent formulation, assay optimization, and validation in clinically relevant matrices such as sputum, urine, stool, or other samples as appropriate.

The role involves close collaboration with Dr. Jeffrey D. Cirillo, laboratory members, and partners in engineering and chemistry. The work integrates biochemistry, chemistry, chemical biology, microbiology, molecular biology, and potentially structural biology to improve assay sensitivity, selectivity, stability, and performance for point-of-care or field-deployable use.

Eligibility highlights: applicants must hold an appropriate PhD in biochemistry, chemistry, chemical biology, structural biology, molecular biology, microbiology, or a closely related field. Preferred experience includes protein purification, biochemical characterization, enzyme kinetics, quantitative data analysis, publication record, beta-lactamases or related enzymes, fluorescence-based assay development, reagent stability testing, FPLC/HPLC, SDS-PAGE, and structural analysis or crystallography. The position also requires strong communication skills, attention to detail, and the ability to work in a BSL-2 environment.

Funding: this is a grant-funded postdoctoral position; continued employment may depend on future funding. Salary is commensurate, and Texas A&M lists standard employee benefits including medical, dental, vision, retirement, paid leave, and tuition assistance.

How to apply: submit an application through the Texas A&M Workday portal. Make sure all application data are completed or attach a complete resume, since incomplete submissions may be rejected. The posting does not list a deadline.

Funding details

This is a grant-funded postdoctoral position. Future employment may be contingent upon future funding. Proposed salary is commensurate. Standard Texas A&M employee benefits are listed, including medical, dental, vision, life, disability, paid leave, retirement, and tuition assistance.

What's required

Applicants must have an appropriate PhD in biochemistry, chemistry, chemical biology, structural biology, molecular biology, microbiology, or a closely related field. Preferred experience includes protein expression and purification, biochemical characterization of proteins or enzymes, enzyme kinetics, quantitative data analysis, publication record, independent research ability, beta-lactamases or related enzyme systems, fluorogenic probe or fluorescence assay development, reagent formulation and stability testing, FPLC/HPLC/SDS-PAGE, structural analysis or crystallography, and assay validation in complex biological matrices. Strong written and verbal communication, presentation skills, analytical skills, attention to detail, and ability to work in a BSL-2 environment are required.

How to apply

Apply through the Texas A&M Workday job portal using the online application. Submit all required job application data or attach a complete resume to avoid rejection. A LinkedIn profile may be used to pre-populate the application.

More information can be found here

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