Publisher
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Pfizer

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Postdoctoral Research Fellow in BioMedicine Design, T Cell Engager and Biotherapeutics Discovery Pfizer in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Full-time fixed-term postdoctoral fellowship for 2–4 years. Annual base salary ranges from $64,600 to $107,600, with eligibility for Pfizer Global Performance Plan bonus target of 7.5% of base salary and comprehensive benefits including retirement contributions, paid leave, and health coverage. Relocation assistance may be available.

Deadline

Oct 13, 2026

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Country

United States

University

Pfizer

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Keywords

Cell Biology
Oncology
Immunology
Molecular Biology
Chemistry
Biomedical Engineering
Biology
Structural Biology
Medical Science
Pharmacy
Protein Engineering

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About this position

Postdoctoral Research Fellow, BioMedicine Design at Pfizer in San Diego, California, United States.

This is a postdoctoral opening in Pfizer’s BioMedicine Design (BMD) / Biotherapeutics Discovery group focused on developing a next-generation T cell engager (TCE) to improve tumor selectivity and reduce on-target, off-tumor toxicity. The role sits at the interface of protein engineering, cell biology, immunology, and oncology, with opportunities to work on antibody discovery and engineering, cellular assays, and preclinical evaluation.

The postdoc will design and produce constructs, develop and use cell-based assays, perform literature-driven hypothesis generation, and communicate results in internal meetings. The program is intended to train the fellow in therapeutic discovery and modality selection, with the goal of preparing them for early-stage drug discovery work and publication in high-impact journals.

Eligibility highlights: PhD in cancer biology, immunology, molecular/cellular biology, biochemistry, chemical and biomolecular engineering, or a related field; less than 2 years of postdoctoral experience; at least one first-author research article; strong hands-on experience with molecular cloning, recombinant protein expression/purification, mammalian cell culture, cell line engineering, transfection, cell-based assays, and flow cytometry. Two recommendation letters are required, including one from the PI and one from an additional professor.

Funding and terms: full-time fixed-term fellowship for 2–4 years. Salary is listed at $64,600–$107,600 annually, plus a bonus target of 7.5% and comprehensive benefits. Relocation assistance may be available. The role is on-premise.

Application window: apply by 2026-10-13. U.S. work authorization is required and visa sponsorship is not available.

Funding details

Full-time fixed-term postdoctoral fellowship for 2–4 years. Annual base salary ranges from $64,600 to $107,600, with eligibility for Pfizer Global Performance Plan bonus target of 7.5% of base salary and comprehensive benefits including retirement contributions, paid leave, and health coverage. Relocation assistance may be available.

What's required

PhD in cancer biology, immunology, molecular or cellular biology, biochemistry, chemical and biomolecular engineering, or a related discipline; less than 2 years of postdoctoral experience; at least one first-author scientific research article in a high-quality journal; two letters of recommendation including one from the PI and one from an additional professor; technical proficiency in construct design, molecular cloning, recombinant protein expression/purification, mammalian cell culture and cell line engineering, transfection and characterization, cell-based assays such as cytotoxicity, proliferation and cytokine production, and flow cytometry; strong data reporting/analysis, planning, organization, problem-solving, analytical, written and oral communication skills; motivation to work in a fast-paced interdisciplinary team.

How to apply

Apply through the Pfizer Careers / Workday posting before October 13, 2026. Include two letters of recommendation with the application, one from your PI and one from an additional professor. Ensure you have permanent work authorization in the United States, as visa sponsorship is not available.

More information can be found here

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