Publisher
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The University of British Columbia

Top university

Postdoctoral Research Fellow in DNA/Aptamer Chemistry and Translational Cancer Research University of British Columbia in Canada

Degree Level

Postdoc

Field of study

Chemistry

Funding

Full-time postdoctoral fellowship/research position for 12 months with the possibility of extension. Expected pay range is $55,000-$65,000 annually.

Deadline

Oct 23, 2026

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Country

Canada

University

The University of British Columbia

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Keywords

Chemistry
Biomedical Engineering
Biology
Cancer Research
Chemical Biology
Medical Science
Prostate Cancer
Nucleic Acid Chemistry

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About this position

Postdoctoral Research Fellow in DNA/Aptamer Chemistry at the University of British Columbia (UBC), Vancouver Campus, Canada.

This opening is in the Perrin Laboratory in the Department of Chemistry, Faculty of Science, and focuses on developing nucleic acid-based targeting agents for prostate cancer. The successful candidate will work on the design, synthesis, modification, purification, and biophysical characterization of DNA aptamers and modified oligonucleotides, with opportunities to contribute to translational cancer research.

Research interests include oligonucleotide/DNA chemistry, solid-phase oligonucleotide synthesis, nucleic acid modification and conjugation, aptamer development or SELEX, protein-ligand binding assays, and analytical/bioanalytical methods such as HPLC, LC-MS, SPR, BLI, MST, and ITC. The role also involves structure-function studies, improving aptamer affinity/selectivity/stability, and conjugating aptamers to imaging or therapeutic payloads.

Applicants must hold a PhD in chemistry, chemical biology, biochemistry, or a closely related field, and should have demonstrated published experience in several of the listed areas. Strong experimental independence and the ability to collaborate across chemistry, biochemistry, structural biology, and imaging are emphasized. Experience with radiochemistry, chelator chemistry, structural biology, or therapeutic oligonucleotide development would be an asset.

The position is full-time for 12 months with the possibility of extension. The expected salary range is $55,000–$65,000 per year. Canadian citizens and permanent residents will be given priority, and UBC notes that members of historically marginalized groups are encouraged to apply.

How to apply: Submit a CV, cover letter, and your legal status to work in Canada via the UBC Workday application portal. Applications are reviewed while the posting remains live; the posting end date is 2026-10-23.

Funding details

Full-time postdoctoral fellowship/research position for 12 months with the possibility of extension. Expected pay range is $55,000-$65,000 annually.

What's required

Applicants must have a PhD in chemistry, chemical biology, biochemistry, or a closely related field. Demonstrated published experience is required in several of the following: oligonucleotide/DNA chemistry, solid-phase oligonucleotide synthesis, nucleic acid modification and conjugation, aptamer development or SELEX, protein-ligand binding assays, and bioanalytical techniques such as SPR, BLI, MST, ITC, HPLC, and LC-MS. Experience with radiochemistry, chelator chemistry, structural biology, or therapeutic oligonucleotide development is an asset. Candidates should be able to independently design and troubleshoot experiments and work collaboratively in a multidisciplinary environment. Canadian citizens and permanent residents are given priority.

How to apply

Submit a CV, cover letter, and your legal status to work in Canada through the UBC Workday application link. Applications are reviewed while the posting remains live, so apply as soon as possible.

More information can be found here

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