Postdoctoral Researcher in Structural Biology and Chromatin Genome Regulation Uppsala University in Sweden

Uppsala University is advertising a postdoctoral researcher in structural biology in the Deindl lab at the Department of Cell and Molecular Biology. The project focuses on chromatin, genome regulation, and the molecular mechanisms that govern the organization and maintenance of chromatin.

The successful candidate will work at the interface of structural biology, molecular biology, and biochemistry, using state-of-the-art cryo-electron microscopy together with biochemical and biophysical approaches. The research aims to uncover how chromatin-associated molecular machines interact with, remodel, and regulate the genome.

The environment is described as vibrant and multidisciplinary, with excellent access to cryo-EM facilities, technical expertise, and infrastructure. The department includes several research programmes spanning computational biology, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology, and structural biology.

Eligibility highlights: applicants should hold a PhD in structural biology, biophysics, biochemistry, molecular biology, or a related field. Prior experience in structural biology is required, including cryo-EM, X-ray crystallography, NMR spectroscopy, integrative structural biology, or related methods. The PhD must be completed by the time the employment decision is made. Preference is given to candidates who earned their PhD no more than three years before the application deadline, unless special circumstances apply. Strong English proficiency, independence, collaboration, self-motivation, and scientific curiosity are expected.

Additional advantages: experience with cryo-EM, in vitro biochemical reconstitution, biophysical analysis, protein purification, protein-DNA complexes, chromatin or nucleosome-based systems, sample preparation, data processing, structure determination, or complementary biophysical methods will strengthen an application.

Employment details: the position is a temporary full-time appointment for two years, with the possibility of extension to three years under the Higher Education Ordinance. The starting date is as soon as possible or as agreed. The position is based in Uppsala, Sweden, and the application deadline is 15 June 2026.

How to apply: submit your application through Uppsala University’s recruitment system before the deadline. For questions about the position, contact Sebastian Deindl at [email protected].