Sebastian Deindl

Uppsala University is advertising a postdoctoral researcher in structural biology in the Deindl lab at the Department of Cell and Molecular Biology . The project focuses on chromatin , genome regulation , and the molecular mechanisms that govern the organization and maintenance of chromatin. The successful candidate will work at the interface of structural biology , molecular biology , biochemistry , and biophysics , using state-of-the-art cryo-electron microscopy together with biochemical and biophysical approaches. The lab aims to uncover how chromatin-associated molecular machines interact with, remodel, and regulate the genome. This position is based in a vibrant structural biology environment with excellent access to cryo-EM facilities, technical expertise, and infrastructure. The department also offers a multidisciplinary research setting spanning computational biology, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology, and structural biology. Eligibility highlights: applicants should hold a PhD in structural biology, biophysics, biochemistry, molecular biology, or a related field. Prior experience with structural biology methods such as cryo-EM, X-ray crystallography, NMR spectroscopy, or integrative structural biology is required. Excellent English proficiency, independence, collaborative skills, scientific curiosity, and a strong interest in basic research are expected. Experience with protein purification, protein-DNA complexes, chromatin or nucleosome-based systems, cryo-EM sample preparation, data processing, structure determination, or complementary biophysical methods is considered an advantage. Employment details: the appointment is temporary for two years, with the possibility of extension to three years. The position is full-time (100%), with salary individually set. The application deadline is 15 June 2026 . How to apply: submit your application through Uppsala University's recruitment system via the official job posting. For further information, contact Sebastian Deindl at [email protected] .

Uppsala University is advertising a postdoctoral researcher in single-molecule biophysics in the Deindl lab at the Department of Cell and Molecular Biology. The project focuses on programmable DNA recognition and genome reorganization , with an emphasis on fundamental mechanisms of molecular specificity, DNA remodeling, and cellular genome dynamics. The successful candidate will use advanced single-molecule fluorescence microscopy together with molecular biology and in vitro biochemistry . The work sits at the interface of biology , physics , and chemistry , and is aimed at answering basic research questions in genome biology using quantitative experimental approaches. The position is hosted by the Department of Cell and Molecular Biology , which includes research programmes in molecular biophysics and related areas. The Deindl laboratory describes itself as a multidisciplinary environment with expertise in biophysics, biochemistry, structural biology, and molecular biology. Eligibility highlights: applicants must hold a PhD in biophysics, biochemistry, physics, molecular biology, cell biology, or a related field. The degree must be completed by the time the employment decision is made. Priority is given to candidates who received their PhD no more than three years before the application deadline, with possible extensions for documented special circumstances. Strong English proficiency, independence, collaboration skills, self-motivation, and interest in basic research are expected. Experience with fluorescence microscopy, single-molecule microscopy, protein-DNA or nucleic acid-protein complexes, genome engineering, or biochemical reconstitution is an advantage. Funding and terms: this is a temporary full-time postdoctoral employment for two years, with the possibility of extension to three years. Salary is individually negotiated. No stipend amount is listed. Application window: apply by 15 June 2026 using Uppsala University’s recruitment system. Reference number: UFV-PA 2026/1516 .

Uppsala University is advertising a postdoctoral researcher in structural biology in the Deindl lab at the Department of Cell and Molecular Biology. The project focuses on chromatin , genome regulation , and the molecular mechanisms that govern the organization and maintenance of chromatin. The successful candidate will work at the interface of structural biology , molecular biology , and biochemistry , using state-of-the-art cryo-electron microscopy together with biochemical and biophysical approaches. The research aims to uncover how chromatin-associated molecular machines interact with, remodel, and regulate the genome. The environment is described as vibrant and multidisciplinary, with excellent access to cryo-EM facilities, technical expertise, and infrastructure. The department includes several research programmes spanning computational biology, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology, and structural biology. Eligibility highlights: applicants should hold a PhD in structural biology, biophysics, biochemistry, molecular biology, or a related field. Prior experience in structural biology is required, including cryo-EM, X-ray crystallography, NMR spectroscopy, integrative structural biology, or related methods. The PhD must be completed by the time the employment decision is made. Preference is given to candidates who earned their PhD no more than three years before the application deadline, unless special circumstances apply. Strong English proficiency, independence, collaboration, self-motivation, and scientific curiosity are expected. Additional advantages: experience with cryo-EM, in vitro biochemical reconstitution, biophysical analysis, protein purification, protein-DNA complexes, chromatin or nucleosome-based systems, sample preparation, data processing, structure determination, or complementary biophysical methods will strengthen an application. Employment details: the position is a temporary full-time appointment for two years, with the possibility of extension to three years under the Higher Education Ordinance. The starting date is as soon as possible or as agreed. The position is based in Uppsala, Sweden, and the application deadline is 15 June 2026 . How to apply: submit your application through Uppsala University’s recruitment system before the deadline. For questions about the position, contact Sebastian Deindl at [email protected].