Postdoctoral Researcher in Structural Biology and Chromatin Genome Regulation Uppsala University in Sweden

Uppsala University is advertising a postdoctoral researcher in structural biology in the Deindl lab at the Department of Cell and Molecular Biology. The project focuses on chromatin, genome regulation, and the molecular mechanisms that govern the organization and maintenance of chromatin.

The successful candidate will work at the interface of structural biology, molecular biology, biochemistry, and biophysics, using state-of-the-art cryo-electron microscopy together with biochemical and biophysical approaches. The lab aims to uncover how chromatin-associated molecular machines interact with, remodel, and regulate the genome.

This position is based in a vibrant structural biology environment with excellent access to cryo-EM facilities, technical expertise, and infrastructure. The department also offers a multidisciplinary research setting spanning computational biology, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology, and structural biology.

Eligibility highlights: applicants should hold a PhD in structural biology, biophysics, biochemistry, molecular biology, or a related field. Prior experience with structural biology methods such as cryo-EM, X-ray crystallography, NMR spectroscopy, or integrative structural biology is required. Excellent English proficiency, independence, collaborative skills, scientific curiosity, and a strong interest in basic research are expected. Experience with protein purification, protein-DNA complexes, chromatin or nucleosome-based systems, cryo-EM sample preparation, data processing, structure determination, or complementary biophysical methods is considered an advantage.

Employment details: the appointment is temporary for two years, with the possibility of extension to three years. The position is full-time (100%), with salary individually set. The application deadline is 15 June 2026.

How to apply: submit your application through Uppsala University's recruitment system via the official job posting. For further information, contact Sebastian Deindl at [email protected].