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Agnieszka Pałucha-Poniewiera

Assisstant Professor

Maj Institute of Pharmacology Polish Academy of Sciences

Poland

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Research Interests

Behavioral Neuroscience

30%

Pharmacology

30%

Neuropharmacology

30%

G Protein-coupled Receptor

30%

Serotonin Research

30%

Neuroplasticity

20%

Psychobiology

10%

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Recent Grants

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Badanie mechanizmów przeciwdepresyjnego działania ligandów II i III grupy receptorów mGlu i ich roli w wywoływaniu szybkiego efektu terapeutycznego w zwierzęcych modelach depresji.

Open Date: 2015-01-23

Close Date: 2018-01-22

Articles8

Depression-like effects induced by chronic unpredictable mild stress in mice are rapidly reversed by a partial negative allosteric modulator of mGlu5 receptor, M-5MPEP

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Year:

2025

(R)-ketamine induces mGlu5 receptor-dependent antidepressant-like effects in the chronic unpredictable mild stress model of depression in mice

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Year:

2025

Subchronic administration of scopolamine reverses UCMS-induced behavior in mice via eEF2 protein dephosphorylation

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Year:

2024

Partial mGlu5 receptor NAM, M-5MPEP, induces rapid and sustained antidepressant-like effects in the BDNF-dependent mechanism and enhances (R)-ketamine action in mice

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Year:

2024

The Antidepressant-like Activity and Cognitive Enhancing Effects of the Combined Administration of (R)-Ketamine and LY341495 in the CUMS Model of Depression in Mice Are Related to the Modulation of Excitatory Synaptic Transmission and LTP in the PFC

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Year:

2023

Combined Administration of (<i>R</i>)-Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Induces Rapid and Sustained Effects in the CUMS Model of Depression via a TrkB/BDNF-Dependent Mechanism

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Year:

2022

The group II mGlu receptor antagonist LY341495 induces a rapid antidepressant-like effect and enhances the effect of ketamine in the chronic unpredictable mild stress model of depression in C57BL/6J mice

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Year:

2021

The influence of the duration of chronic unpredictable mild stress on the behavioural responses of C57BL/6J mice

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Year:

2020

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