Bishoy Morris Faltas

The Faltas Lab at Weill Cornell Medicine in New York City is seeking outstanding postdoctoral researchers to join their team in studying the mechanisms of cancer evolution and developing strategies to intercept them. The lab focuses on cutting-edge research areas including APOBEC3 mutagenesis and RNA editing, extrachromosomal DNA and drug resistance, noncoding genome in tumor evolution, AI-driven bio-digital avatars, and translational drug development. The research leverages patient-derived organoids, advanced mouse models, and computational approaches to understand how tumors diversify, resist therapy, and metastasize. The lab is collaborative, well-funded, and offers a supportive environment for career development. Funding is stable and long-term, supported by NCI R37 MERIT, with compensation above standard NIH postdoc rates. Benefits include full health and dental insurance and subsidized NYC housing. The principal investigator, Dr. Bishoy Morris Faltas, is committed to investing in the career growth of lab members. Applicants should have a PhD in molecular biology, cell biology, biochemistry, pharmacology, or a related field, with a strong mechanistic understanding of biology. Bench skills such as cloning, westerns, qPCR, and cell culture, as well as a solid publication record, are valued. Mouse experience and computational skills (R/Python) are a plus but not required. The ideal candidate is driven, thinks deeply about biological mechanisms, and is motivated to make a difference in cancer treatment. To apply, candidates should send their CV, research statement, publications, and three references to Dr. Bishoy M. Faltas at [email protected]. This is an excellent opportunity for postdoctoral researchers interested in cancer evolution, translational research, and computational biology to join a leading institution and contribute to impactful science.

Postdoctoral positions available at Weill Cornell Medicine in the Faltas Lab, led by Dr. Bishoy M. Faltas, Chief Research Officer at the Englander Institute for Precision Medicine and Associate Professor of Medicine and Cell and Developmental Biology. The lab studies the mechanisms of cancer evolution and how to intercept them, with a strong focus on bladder cancer and related systems. Research integrates patient-derived samples, organoids, mouse models, genomics, and computational approaches to understand how tumors diversify, adapt, resist therapy, and metastasize. Current areas of interest include APOBEC-driven mutagenesis , DNA repair , synthetic lethal vulnerabilities , extrachromosomal DNA , the noncoding genome , tumor evolution under therapeutic pressure, and AI-enabled translational models. This is a postdoctoral researcher / research associate opportunity for scientists who want to do more than perform experiments: the lab is looking for people who can turn ideas into executable plans, respond to feedback, and communicate clearly. Strong candidates will have experience in cancer biology, molecular biology, cell biology, biochemistry, pharmacology, genomics, or a related field. Mouse work and computational skills are welcome but not required. First-author publications in competitive peer-reviewed journals are especially valued. The position is described as well-funded and collaborative, with above-NIH salary , full benefits , subsidized New York City housing , and strong support for scientific and career development. How to apply: email Dr. Bishoy M. Faltas with a CV, cover letter, relevant publications or preprints, three references, and a one-page document answering two prompts: (1) a biological question you would pursue in the lab, your first experiment, and the biggest conceptual risk; and (2) one technically difficult experiment or project you personally drove, what went wrong, how you troubleshot it, and what you learned. No deadline is stated in the post.