Claudiu T Supuran

University of Florence

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Articles (31)

Collaborators (17)

Daniel Flaherty

Associate Professor

Purdue University

UNITED STATES

Paola Gratteri

Associate Professor

University of Firenze

Letizia GIAMPIETRO

Associate Professor

University of Chieti-Pescara

Ashok Aspatwar

Adjunct Professor

Fawzy Elbarbry

Professor, Director of Student Success

Pacific University

UNITED STATES

Antonello Mai

Sapienza University of Rome

Mattia Mori

Associate Professor

University of Siena

Mariangela Agamennone

Associate professor

University of Chieti-Pescara

Marta Ferraroni

University of Florence

Seppo Parkkila

University of Tampere

Cristina MACCALLINI

Associate Professor

University “G. d’Annunzio” of Chieti-Pescara

Ilaria D'Agostino

University of Pisa

Gyochang Keum

University of Science and Technology (UST)

Dante Rotili

Sapienza University of Rome

Andrea Angeli

University of Florence

Shoukat Dedhar

The University of British Columbia

Rossella Grande

Claudiu T Supuran

Research Interests

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Contact this professor

Articles (31)

Design and Synthesis of 2-substituted [1,2,4]Triazolo[1,5-a]pyrimidines Tethered with Umbelliferone as Selective Carbonic Anhydrase IX and XII Inhibitors

Hybrid and Chimeric Heterocycles for the Inhibition of Carbonic Anhydrases

Human Carbonic Anhydrase Inhibitors

Green Synthesis of Sulfonamide Derivatives as Human Carbonic Anhydrase Isoforms I, II, IX, XII Inhibitors and Antioxidants: Comprehensive Insights From Biological Evaluation and In‐Depth In Silico Analysis

Human carbonic anhydrase modulators: the past, present, and future

Unveiling the Carbonic Anhydrase Inhibitory Profile of Aprocitentan: Kinetic and Structural Characterization

Novel Taurinamide‐Based Compounds as Carbonic Anhydrase Inhibitors

Exploration of 3‐Substituted Benzofuran‐Tethered Sulfamoyl Triazoles as Carbonic Anhydrase Inhibitors: Design, Synthesis, and Biological Evaluation

Development of a New AMBER Force Field for Cysteine and Histidine Cadmium‐Binding Proteins and Its Validation Through QM/MM MD Simulations

Unraveling the Potential of Amino-, Acylamino-, and Ureido-Substituted 3H-1,2-Benzoxaphosphepine 2-Oxides toward Nanomolar Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII

Azobenzenesulfonamide Carbonic Anhydrase Inhibitors as New Weapons to Fight Helicobacter pylori: Synthesis, Bioactivity Evaluation, In Vivo Toxicity, and Computational Studies

A comprehensive investigation of the anion inhibition profile of a β-carbonic anhydrase from Acinetobacter baumannii for crafting innovative antimicrobial treatments

Cloning, expression, and purification of an α-carbonic anhydrase from Toxoplasma gondii to unveil its kinetic parameters and anion inhibition profile.

Synthesis, carbonic anhydrase inhibition studies and modelling investigations of phthalimide–hydantoin hybrids

Physiological modeling of the metaverse of the Mycobacterium tuberculosis β-CA inhibition mechanism

Hydrogen Sulfide-Releasing Carbonic Anhydrase Inhibitors Effectively Suppress Cancer Cell Growth

Harnessing Nitric Oxide-Donating Benzofuroxans for Targeted Inhibition of Carbonic Anhydrase IX in Cancer

Optimization of Ethoxzolamide Analogs with Improved Pharmacokinetic Properties for In Vivo Efficacy against Neisseria gonorrhoeae

Inhibitory Effect of Two Carbonic Anhydrases Inhibitors on the Activity of Major Cytochrome P450 Enzymes

Synthesis and Carbonic Anhydrase I, II, IX, and XII Inhibition Studies with a Series of Cyclic Sulfonyl Guanidines

Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII

Cloning, characterization, and inhibition of the novel β-carbonic anhydrase from parasitic blood fluke, Schistosoma mansoni

A well-trained and well-organised scientific method is what science is

Erlotinib-containing benzenesulfonamides as anti-<i>Helicobacter pylori</i> agents through carbonic anhydrase inhibition

Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors

2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors

Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII

Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII

Carbonic anhydrase inhibitory activity of phthalimide-capped benzene sulphonamide derivatives

Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II

Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors

Collaborators (17)

Daniel Flaherty

Paola Gratteri

Letizia GIAMPIETRO

Ashok Aspatwar

Fawzy Elbarbry

Antonello Mai

Mattia Mori

Mariangela Agamennone

Marta Ferraroni

Seppo Parkkila

Cristina MACCALLINI

Ilaria D'Agostino

Gyochang Keum

Dante Rotili

Andrea Angeli

Shoukat Dedhar

Rossella Grande

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