Elisa Fadda

PhD opportunity in structural biology , glycobiology , biochemistry , biophysics , and computational biology at ESRF - The European Synchrotron (Grenoble, France) in collaboration with the Institute for Life Sciences, University of Southampton (UK). The project focuses on a problem in modern structural biology workflows: glycans are often removed or ignored, even though glycosylation strongly affects how many therapeutic proteins bind their targets. The successful PhD student will develop a computational pipeline to resolve glycan conformation and occupancy directly from solution scattering data. The work combines glycosylation prediction, ensemble generation, and SWAXS-based scoring, and will be validated on real therapeutic and vaccine-relevant systems such as antibodies and viral envelope immunogens. This is a 4-year position split between France and the UK, offering experience across wet-lab, computational, and large-scale facility environments. The supervisory team includes Hayden Fisher, Elisa Fadda, Ivo Tews, Joel Allen, and Abigail Sudol. Applicants should have a strong foundation in biochemistry , biophysics , or structural biology , plus curiosity about integrative approaches and comfort with scientific programming. The post is especially relevant for students interested in protein structure, glycosylation, solution scattering, and translational biomolecular research. How to apply: read the full details via the application link and follow the instructions in the linked post. No deadline is stated in the post.