Han Chen

Has grant

Associate Professor

The University of Texas Health Science Center at Houston School of Public Health

United States

Research Interests

Explore related searches

Professors in United States Professors in Medical Science Medical Science professors in United States

Contact this professor

ORCID

Google Scholar

About

Han Chen is an Associate Professor at The University of Texas Health Science Center at Houston School of Public Health, USA. His research areas encompass genetic architecture, genome-wide analyses, and pharmacogenomics, with a focus on precision medicine and chronic diseases. Recent publications include studies on circulating metabolites, gene-sleep interactions, and the prediction of neurotoxicity in pediatric leukemia patients.

Recent Grants

Grant: Close

Methods and Software for Large-Scale Gene-Environment Interaction Studies

Open Date: 2019-07-15

Close Date: 2024-06-30

Grant: Close

Statistical and Computational Methods for Large-Scale Sequencing Studies

Open Date: 2016-12-19

Close Date: 2019-11-30

Grant: Close

Statistical and Computational Methods for Large-Scale Sequencing Studies

Open Date: 2016-12-01

Close Date: 2020-11-01

Grant: Close

Statistical and Computational Methods for Large-Scale Sequencing Studies

Open Date: 2015-12-15

Close Date: 2016-11-30

Grant: Close

Statistical and Computational Methods for Large-Scale Sequencing Studies

Open Date: 2015-12-15

Close Date: 2017-11-30

Han Chen

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (30)

A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations

A multi-level gene-diet interaction analysis of fish oil and 14 polyunsaturated fatty acid traits identifies the FADS and GPR12 loci

A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.

Evaluation of methotrexate Pharmacogenomic variation to predict acute neurotoxicity in children with acute lymphoblastic leukemia

Prediction of methotrexate neurotoxicity using clinical, sociodemographic, and area-based information in children with acute lymphoblastic leukemia

Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program.

Genome-wide Gene by Sleepiness Interaction Analysis for Sleep Apnea.

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.

A Biomarker Signature-Guided Clinical Trial Design for Precision Medicine.

FedGMMAT: Federated generalized linear mixed model association tests.

iGWAS: Image-based genome-wide association of self-supervised deep phenotyping of retina fundus images.

X-linked genetic associations in sporadic thoracic aortic dissection.

Unsupervised deep representation learning enables phenotype discovery for genetic association studies of brain imaging.

Metabolomic profiles of sleep-disordered breathing are associated with hypertension and diabetes mellitus development.

Genome-Wide Interaction Analysis With DASH Diet Score Identified Novel Loci for Systolic Blood Pressure.

Analyzing longitudinal trait trajectories using GWAS identifies genetic variants for kidney function decline.

Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program.

FiMAP: A fast identity-by-descent mapping test for biobank-scale cohorts.

Re-analysis and meta-analysis of summary statistics from gene-environment interaction studies.

Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis.

Exploiting family history in aggregation unit-based genetic association tests

Metabolomic Associations of Asthma in the Hispanic Community Health Study/Study of Latinos

GEM: scalable and flexible gene-environment interaction analysis in millions of samples.

Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function.

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Estimation of total mediation effect for high-dimensional omics mediators.

Genome-wide gene-diet interaction analysis in the UK Biobank identifies novel effects on hemoglobin A1c.

Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.

Birth defect co-occurrence patterns in the Texas Birth Defects Registry.

Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study.

Collaborators (18)

L. Adrienne Cupples

Amy Bentley

Zhe Wang

Luca Giancardo

Victoria Jackson

zekai chen

Mark Zobeck

Gina Peloso

Assaf Gottlieb

Josee Dupuis

Jenna Carlson

Kari North

Joanne Curran

Albert Vernon Smith

Anita DeStefano

Peng Wei

Kaixiong Ye

Laura Mitchell

How do I reach out?

Meet Kite AI