Jack Mellor

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University of Bristol

United Kingdom

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Recent Grants

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Regulation of microRNA-mediated local translation in neurons by Argonaute phosphorylation

Open Date: 2018-07-03

Close Date: 2021-07-02

Grant: Close

Neural adaptation to sensory stimuli by regulation of dendritic spikes and synaptic plasticity.

Open Date: 2018-01-01

Close Date: 2021-09-29

Grant: Close

Plasticity of inhibitory synaptic transmission in the hippocampus

Open Date: 2016-09-30

Close Date: 2019-09-29

Grant: Close

PICK1 and cortactin as antagonistic regulators of Arp2/3-mediated actin polymerisation in GluA2-dependent AMPA receptor trafficking.

Open Date: 2014-06-22

Close Date: 2017-06-21

Grant: Close

The role of acetylcholine in hippocampal function.

Open Date: 2014-04-09

Close Date: 2020-08-22

Articles (15)

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2024

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2022

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2021

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2021

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2021

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2021

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2021

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UNITED KINGDOM

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Jeremy Henley

University of Bristol

UNITED KINGDOM

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Kerrie Thomas

Reader

Cardiff University

UNITED KINGDOM

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FRANCE

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Dominic Dwyer

Professor

Cardiff University

UNITED KINGDOM

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Emma Robinson

Professor of Psychopharmacology

University of Bristol

UNITED KINGDOM

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Mohammed Elasrag

The University of Manchester

UNITED KINGDOM

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Matt Jones

UNITED KINGDOM

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Elek Molnár

University of Bristol

UNITED KINGDOM

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James Rouse

Teaching Fellow

University of Leeds

UNITED KINGDOM

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Lu-Yang Wang

Assistant, Associate & Full Professor

University of Toronto

CANADA

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Jack Mellor

Research Interests

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Recent Grants

Articles (15)

APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors

Hippocampal-dependent navigation in head-fixed mice using a floating real-world environment

The importance of memory in severe mental illness

A mild impairment in reversal learning in a bowl‐digging substrate deterministic task but not other cognitive tests in the Dlg2+/− rat model of genetic risk for psychiatric disorder

GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors

Reduced expression of the psychiatric risk gene DLG2 (PSD93) impairs hippocampal synaptic integration and plasticity

Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder

PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies

21st century excitatory amino acid research

Investigation of reward learning and feedback sensitivity in non-clinical participants with a history of early life stress

Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits

Acetylcholine Boosts Dendritic NMDA Spikes in a CA3 Pyramidal Neuron Model.

Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD

Interneuron-specific plasticity at parvalbumin and somatostatin inhibitory synapses onto CA1 pyramidal neurons shapes hippocampal output

Noradrenaline release from Locus Coeruleus terminals in the hippocampus enhances excitation-spike coupling in CA1 pyramidal neurons via β-adrenoceptors

Collaborators (19)

Simonas Griesius

David Wyllie

Kevin Wilkinson

Cian O'Donnell

Chloe Slaney

Jeremy Henley

Kerrie Thomas

Zafar Bashir

Michael Ashby

Angela Mabb

Amanda Bretman

Sebastien Moreno

Dominic Dwyer

Emma Robinson

Mohammed Elasrag

Matt Jones

Elek Molnár

James Rouse

Lu-Yang Wang

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