Jack Mellor at University of Bristol - Research Interests, Publications & Academic Profile

Jack Mellor

University of Bristol

United Kingdom

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Research Interests

Computational Neuroscience

50%

Cognitive Neuroscience

40%

Neurochemistry

60%

Neuroscience

60%

Synaptic Biology

60%

Basal Ganglia

30%

Neuroplasticity

30%

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Recent Grants

Grant: Close

Regulation of microRNA-mediated local translation in neurons by Argonaute phosphorylation

Open Date: 2018-07-03

Close Date: 2021-07-02

Grant: Close

Neural adaptation to sensory stimuli by regulation of dendritic spikes and synaptic plasticity.

Open Date: 2018-01-01

Close Date: 2021-09-29

Grant: Close

Plasticity of inhibitory synaptic transmission in the hippocampus

Open Date: 2016-09-30

Close Date: 2019-09-29

Grant: Close

PICK1 and cortactin as antagonistic regulators of Arp2/3-mediated actin polymerisation in GluA2-dependent AMPA receptor trafficking.

Open Date: 2014-06-22

Close Date: 2017-06-21

Grant: Close

The role of acetylcholine in hippocampal function.

Open Date: 2014-04-09

Close Date: 2020-08-22

Articles15

APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors

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Year:

2024

Hippocampal-dependent navigation in head-fixed mice using a floating real-world environment

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Year:

2024

The importance of memory in severe mental illness

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Year:

2024

A mild impairment in reversal learning in a bowl‐digging substrate deterministic task but not other cognitive tests in the Dlg2+/− rat model of genetic risk for psychiatric disorder

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Year:

2023

GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors

Article Link

Year:

2023

Reduced expression of the psychiatric risk gene DLG2 (PSD93) impairs hippocampal synaptic integration and plasticity

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Year:

2022

Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder

Article Link

Year:

2022

PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies

Article Link

Year:

2022

21st century excitatory amino acid research

Article Link

Year:

2021

Investigation of reward learning and feedback sensitivity in non-clinical participants with a history of early life stress

Article Link

Year:

2021

Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to CA1 by differential modulation of feedforward inhibitory circuits

Article Link

Year:

2021

Acetylcholine Boosts Dendritic NMDA Spikes in a CA3 Pyramidal Neuron Model.

Article Link

Year:

2021

Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD

Article Link

Year:

2021

Interneuron-specific plasticity at parvalbumin and somatostatin inhibitory synapses onto CA1 pyramidal neurons shapes hippocampal output

Article Link

Year:

2020

Noradrenaline release from Locus Coeruleus terminals in the hippocampus enhances excitation-spike coupling in CA1 pyramidal neurons via β-adrenoceptors

Article Link

Year:

2020

Collaborators16

Simonas Griesius

University of Bristol

UNITED KINGDOM

David Wyllie

Professor

University of Edinburgh

UNITED KINGDOM

Cian O'Donnell

Lecturer in Data Analytics

University of Ulster

UNITED KINGDOM

Chloe Slaney

University of Bristol

UNITED KINGDOM

Jeremy Henley

University of Bristol

UNITED KINGDOM

Kerrie Thomas

Reader

Cardiff University

UNITED KINGDOM

Zafar Bashir

University of Bristol

UNITED KINGDOM

Michael Ashby

Academic , Senior Lecturer

University of Bristol

UNITED KINGDOM

Angela Mabb

Associate Professor

University of Georgia

UNITED STATES

Dominic Dwyer

Professor

Cardiff University

UNITED KINGDOM

Emma Robinson

Professor of Psychopharmacology

University of Bristol

UNITED KINGDOM

Mohammed Elasrag

The University of Manchester

UNITED KINGDOM

Matt Jones

UNITED KINGDOM

Elek Molnár

University of Bristol

UNITED KINGDOM

James Rouse

Teaching Fellow

University of Leeds

UNITED KINGDOM

Lu-Yang Wang

Assistant, Associate & Full Professor

University of Toronto

CANADA

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