Post-doctoral fellow in cancer metabolism
Post-doctoral fellow in cancer metabolism
at
Inserm U1065
/
Centre Méditerranéen de Médecine Moléculaire (C3M)
in Nice, France.
The research team
Metabolism, Cancer and immune responses
, led by
Jean-Ehrland Ricci
, is recruiting a full-time, fixed-term postdoctoral fellow for a three-year project focused on cancer metabolism, mitochondrial biology, DNA damage responses, and therapeutic resistance in malignant B cells.
The project investigates how the chemotherapeutic agent
L-asparaginase (ASNase)
rewires tumor metabolism across mitochondria, cytosol, and nucleus, and how these changes promote oxidative stress, redox imbalance, DNA damage, replication stress, and repair pathway alterations. The work uses a validated B-cell lymphoma model of secondary ASNase resistance and combines genetic and pharmacological tools with confocal imaging, flow cytometry, metabolomics, proteomics, stable-isotope tracing, and in vitro/in vivo validation.
The host team offers a highly interactive environment with expertise in cancer biology, metabolism, and immunology, and the successful candidate will contribute to an INCa PLBIO-funded project in collaboration with partners in Lyon and Paris.
Eligibility highlights:
PhD in cancer biology or metabolism, or near submission; strong experience in cell biology, molecular biology, metabolism, and cancer research; metabolomics and omics analysis skills; excellent English communication; ability to work independently and collaboratively. Experience with mouse models is desirable, and animal experimentation certification is preferred but not required.
Funding and benefits:
salary according to experience or €35,268 per year (taxes included), approximately €2,939 gross per month, plus employer-supported health insurance, optional retirement plan contribution, partial public transport reimbursement, and access to a company cafeteria.
Application:
apply by email with a CV, motivation letter, and at least two recommendation letters. Deadline:
30 October 2026, 17:00 (Europe/Paris)
.
