Jing Wang

Professor

University Name

United States

Research Interests

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Professor Jing Wang is a faculty member at the UPMC Hillman Cancer Center, University of Pittsburgh, USA. Her research focuses on cancer immunotherapy and the immune microenvironment, particularly in the context of head and neck squamous cell carcinoma and therapeutic responses to various treatments. Recent publications include studies on myeloid cell targeting, T cell responses, and the signaling mechanisms in B cells that influence treatment efficacy.

Articles (12)

MHC class I upregulation contributes to the therapeutic response to radiotherapy in combination with anti-PD-L1/anti-TGF-β in squamous cell carcinomas with enhanced CD8 T cell memory-driven response

Year:

2025

Targeting Myeloid Cells in Head and Neck Squamous Cell Carcinoma: A Kinase Inhibitor Library Screening Approach

Year:

2024

Cetuximab Responses in Patients with HNSCC Correlate to Clonal Expansion Feature of Peripheral and Tumor-Infiltrating T Cells with Top T-Cell Receptor Clonotypes

Year:

2023

Pharmacologic targeting of Nedd8-activating enzyme reinvigorates T-cell responses in lymphoid neoplasia.

Year:

2023

TRAF2/3 deficient B cells resist DNA damage-induced apoptosis via NF-κB2/XIAP/cIAP2 axis and IAP antagonist sensitizes mutant lymphomas to chemotherapeutic drugs

Year:

2023

Inducible nitric oxide synthase (iNOS)-activated Cxcr2 signaling in myeloid cells promotes TGFβ-dependent squamous cell carcinoma lung metastasis

Year:

2023

How the Signaling Crosstalk of B Cell Receptor (BCR) and Co-Receptors Regulates Antibody Class Switch Recombination: A New Perspective of Checkpoints of BCR Signaling.

Year:

2021

Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts.

Year:

2021

Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.

Year:

2021

Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFβ/PD-L1 blockade-treated squamous cell carcinoma.

Year:

2021

Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15<sup>+</sup> Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma.

Year:

2020

Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft.

Year:

2020

Collaborators (8)

Canping Chen

Oregon Health & Science University

UNITED STATES

Jennifer Diamond

Associate Professor

University of Colorado Anschutz Medical Campus

UNITED STATES

Huaibin Ge

University of Pittsburgh

UNITED STATES

Brian Freed

Professor of Medicine and Immunology

University of Colorado Anschutz Medical Campus

UNITED STATES

Nathan Pennock

Research Assistant Professor

Oregon Health & Science University

UNITED STATES

John Morton

Assistant Research Professor

University of Colorado Anschutz Medical Campus

UNITED STATES

Robert Ferris

UPMC Endowed Professor

University of Pittsburgh School of Medicine

UNITED STATES

Zhangguo Chen

Research Associate Professor

UPMC Hillman Cancer Center

UNITED STATES

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