Postdoctoral Researcher in Structural Biology of Mitochondrial Gene Expression
Karolinska Institutet invites applications for a postdoctoral position in structural biology, focusing on mitochondrial gene expression and translation in health and disease. The successful candidate will join the laboratory of Professor Joanna Rorbach at the Department of Medical Biochemistry and Biophysics, located in Biomedicum, Solna, Stockholm, Sweden. The Rorbach group investigates mitochondrial gene regulation using genetic, structural, biochemical, and molecular approaches, with a strong emphasis on disease-relevant mechanisms and therapeutic opportunities. Recent publications from the group highlight their expertise in Nature Reviews Molecular Cell Biology, Nature Communications, and Nature.
The project integrates structural biology, mitochondrial biology, molecular biology, and disease modelling to elucidate how mitochondrial proteins regulate gene expression and contribute to mitochondrial disease. The candidate will employ advanced molecular and structural techniques, including cryo-EM, to uncover new insights into protein function and disease pathophysiology. The research environment is creative, collaborative, and international, with English as the working language.
Applicants should have a PhD in structural biology, molecular biology, biochemistry, biophysics, or a related field, with strong practical experience in cryo-EM and molecular biology. Previous experience in mitochondrial biology is desirable. Candidates must demonstrate excellent knowledge of modern biological and structural approaches, a promising publication record, rigorous scientific mindset, good documentation and organizational skills, and proficiency in English. The ability to work independently and collaboratively is essential. Completion of the doctoral degree within the last three years is advantageous, but earlier completion may be accepted for special reasons. Eligibility requires a PhD or equivalent foreign degree, fulfilled by the time of employment decision.
The position offers either a monthly salary or a tax-free scholarship for up to two years, paid out on a six months basis. Eligible candidates may be offered a postdoctoral scholarship, which promotes internationalization and research qualification after a doctorate. Karolinska Institutet provides access to state-of-the-art infrastructure, including facilities for cryo-EM, advanced microscopy, flow cytometry, next-generation sequencing, and transgenic technologies. The university is renowned for its medical research and education, offering a stimulating environment with wide-ranging expertise and opportunities for interdisciplinary collaboration.
Applications must be submitted through the Varbi recruitment system. Required documents include a PhD certificate, complete resumé (with thesis details, academic positions, distinctions, and committee work), publication list, cover letter describing research experience and motivation, and contact details for two referees. Salary is set individually according to collective agreements. The deadline for applications is July 1, 2026. For further information, contact Professor Joanna Rorbach at [email protected].
