Klaus Eyer

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Associate Professor

Aarhus University
Country flagDenmark

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About

Klaus Eyer is an Associate Professor at Aarhus University in Denmark. His research focuses on single-cell analysis, with recent articles exploring topics such as antibody secretion, cytokine release dynamics, and the functional heterogeneity of immune cells. He is particularly interested in the development of innovative microfluidic platforms for studying immune responses and the quantitative assessment of immunization effects.

Recent Grants

Grant: Close

New bridges across the translational gap

Open Date: 2019-09-01

Close Date: 2021-08-01

Grant: Close

High-throughput single-cell phenotypic analysis of functional antibody repertoires

Open Date: 2019-02-01

Close Date: 2024-01-31

Grant: Close

Functional high-throughput single-cell analysis towards the rational development of new vaccines

Open Date: 2016-09-01

Close Date: 2021-09-01

Grant: Close

Time resolved ultrahigh resolution phenotypic mapping of antibody producing cells

Open Date: 2016-09-01

Close Date: 2018-02-28

Grant: Close

Detection of circulating tumor cells in patients

Open Date: 2016-05-01

Close Date:

Positions (2)

Publisher
source

Klaus Eyer

University Name
.

Aarhus University

The MSCA-DN TRANSCEND network, coordinated by Associate Professor Klaus Eyer at Aarhus University, is recruiting two doctoral students for cutting-edge research in multiple sclerosis (MS). The first PhD position focuses on deep-phenotyping of anti-lipid autoantibodies in MS at the single-antibody level, with collaborative research exchanges in Milan under the supervision of Dr. Daniela Latorre, an expert in autoreactive T cells. The second PhD position centers on functional multiomic profiling of circulating immune cells in MS, including a research stay at Amsterdam UMC with Dr. Gijs Kooij, a specialist in MS and inflammation. TRANSCEND is a transdisciplinary network aiming to revolutionize translational research for complex conditions, integrating science, philosophy, and patient-centered care. Applicants should have a relevant master's degree and a strong background in immunology, molecular biology, or neuroscience. Both positions are fully funded and offer international research opportunities. Applications must be submitted via the provided links by October 30, 2024. For more information, visit the TRANSCEND network page and the Euraxess platform.

1 year ago

Publisher
source

Klaus Eyer

University Name
.

Aarhus University

Open fully financed PhD position at Aarhus University , Department of Biomedicine, in a project on single-cell analysis of autoreactive antibody repertoires . The research will investigate the diversity, specificity, and function of autoreactive antibodies at single-cell resolution. The project combines immunology , antibody biology , single-cell technologies , and data science , with a strong translational angle and collaboration with clinical partners. This is a good fit for candidates interested in Biology , Medical Science , and related biomedical methods. The position is supported by funding from the Independent Research Fund Denmark . Deadline: 25 September 2026. Preferred start: 1 December 2026 (negotiable). Applications must be submitted through the official application portal; the poster explicitly says no applications by email . The poster also invites interested applicants to reach out with questions.

1 month ago

Articles (10)

Year:

2023

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2023

Increasing evidence suggests that natural killer (NK) cells are composed of distinct functional subsets. This multifunctional role has made them an attractive choice for anticancer immunotherapy. A functional NK cell repertoire is generated through cellular education, resulting in a heterogeneous NK cell population with distinct capabilities responding to different stimuli. The application of a high‐throughput droplet‐based microfluidic platform allows monitoring of NK cell‐target cell interactions at the single‐cell level and in real‐time. A variable response of single NK cells toward different target cells is observed, and a distinct population of NK cells (serial killers) capable of inducing multiple target lysis is identified. By assessing the cytotoxic dynamics, it is shown that single umbilical cord blood‐derived CD34+ hematopoietic progenitor (HPC)‐NK cells display superior antitumor cytotoxicity. With an integrated analysis of cytotoxicity and cytokine secretion, it is shown that target cell interactions augment cytotoxic as well as secretory behavior of NK cells. By providing an integrated assessment of NK cell functions by microfluidics, this study paves the way to further functionally characterize NK cells ultimately aimed to improve cancer immunotherapy.

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2022

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2022

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (4)

Jean Baudry

-

FRANCE
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Paul de Jonge

Senior Scientist & Deputy Head Cell Therapy Facility

Radboudumc

NETHERLANDS
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Mark van Turnhout

Eindhoven University of Technology

NETHERLANDS
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Jurjen Tel

-

NETHERLANDS
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