Roel Vermeulen
Professor
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Positions (7)
Articles (20)
The ethical aspects of exposome research: a systematic review
In recent years, exposome research has been put forward as the next frontier for the study of human health and disease. Exposome research entails the analysis of the totality of environmental exposures and their corresponding biological responses within the human body. Increasingly, this is operationalized by big-data approaches to map the effects of internal as well as external exposures using smart sensors and multiomics technologies. However, the ethical implications of exposome research are still only rarely discussed in the literature. Therefore, we conducted a systematic review of the academic literature regarding both the exposome and underlying research fields and approaches, to map the ethical aspects that are relevant to exposome research. We identify five ethical themes that are prominent in ethics discussions: the goals of exposome research, its standards, its tools, how it relates to study participants, and the consequences of its products. Furthermore, we provide a number of general principles for how future ethics research can best make use of our comprehensive overview of the ethical aspects of exposome research. Lastly, we highlight three aspects of exposome research that are most in need of ethical reflection: the actionability of its findings, the epidemiological or clinical norms applicable to exposome research, and the meaning and action–implications of bias.
Year:
2023
Collaborators (14)
Maarten van Smeden
Associate professor
University Medical Center Groningen
Mariana Simões
Utrecht University
Ulrike Gehring
Utrecht University
Anke Huss
-
Annelien L Bredenoord
University Medical Center Groningen
Beata Swiatkowska
Assistant Professor
Medical University of Lodz
Tiina Santonen
Finnish Institute of Occupational Health
John Field
Clinical Professor of Molecular Oncology
-
Luoping Zhang
University of California
Benjamin Kendzia
Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr Univer
Esmeralda Krop
Utrecht University
Susan Peters
Assistant Professor
Utrecht University
Ingvar Bergdahl
Lecturer
Umea University
Judith Vonk
University Medical Center Groningen

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