Tobias Giessen

Assistant Professor

University of Michigan Medical School

United States

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Dr. Tobias Giessen is an Assistant Professor at the University of Michigan Medical School in the United States. His research focuses on the structural and biochemical characterization of protein nanocompartments, particularly encapsulins, and their applications in drug delivery. His recent publications include studies on the diverse structural properties of encapsulin protein shells and the engineering of nanocages for enzyme performance enhancement.

Tobias Giessen

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Articles (21)

A Two‐Component Pseudo‐Icosahedral Protein Nanocompartment with Variable Shell Composition and Irregular Tiling

Encapsulins: catalysis inside a shell

Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin

Engineering encapsulin nanocages for drug delivery

Pore Engineering as a General Strategy to Improve Protein-Based Enzyme Nanoreactor Performance

Structural and biochemical characterization of an encapsulin‐associated rhodanese from Acinetobacter baumannii

Cyclodipeptide oxidase is an enzyme filament

Structural basis for peroxidase encapsulation inside the encapsulin from the Gram-negative pathogen Klebsiella pneumoniae

A widespread bacterial protein compartment sequesters and stores elemental sulfur

The Structural Diversity of Encapsulin Protein Shells

The biosynthesis of the odorant 2-methylisoborneol is compartmentalized inside a protein shell

Exploring the Extreme Acid Tolerance of a Dynamic Protein Nanocage

Encapsulin cargo loading: progress and potential

Pore structure controls stability and molecular flux in engineered protein cages

Engineered Protein Nanocages for Concurrent RNA and Protein Packaging In Vivo

In Vitro Synthesis and Reconstitution Using Mammalian Cell-Free Lysates Enables the Systematic Study of the Regulation of LINC Complex Assembly

Encapsulins.

Heterologous expression and purification of encapsulins in Streptomyces coelicolor

Triggered Reversible Disassembly of an Engineered Protein Nanocage**

Triggered Reversible Disassembly of an Engineered Protein Nanocage**

Large-scale computational discovery and analysis of virus-derived microbial nanocompartments

Collaborators (3)

Jesse Jones

Yu Heng Lau

Allen Liu

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