Vivian G. Cheung

The Cheung Lab at the Warren Alpert Medical School of Brown University is seeking a Postdoctoral Fellow to lead a cutting-edge project at the intersection of RNA biology and neuroscience. The lab, directed by Professor Vivian G. Cheung, focuses on understanding how transcriptional and co-transcriptional mechanisms regulate brain function and contribute to neurological diseases such as ALS and Alzheimer's Disease. The research leverages human iPSC-derived tri-culture brain organoids, including neurons, astrocytes, and microglia, to study RNA-based regulatory processes in a physiologically relevant human system. As part of the Human RNome Project Consortium, the lab is engaged in international efforts to define and sequence human RNA in its full chemical complexity. The multidisciplinary team integrates human genetics, molecular biology, and computational approaches to advance fundamental RNA discovery and address mechanistic questions in brain biology. The lab values diversity, mentorship, and scientific independence, providing a supportive environment for postdoctoral researchers. The ideal candidate will have a strong background in RNA biology, with expertise in transcriptional regulation, RNA processing, RNA modifications, R-loops, or related mechanisms. Proficiency in human molecular biology is required, and experience with iPSCs or organoids is considered an asset. Quantitative fluency and the ability to incorporate computational, mathematical, or statistical methods into experimental design and analysis are highly valued. While specific funding details are not provided, the position is a postdoctoral fellowship at Brown University, typically including salary and benefits. Interested candidates should apply via the provided Interfolio link and prepare application materials as outlined on the application portal. For more information about the lab and its research, visit the Cheung Lab website.