Sérgio Filipe Sousa
4 months ago
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La Caixa Foundation
PhD Studentship in Computational Drug Discovery for Machado-Joseph Disease University of Porto in Portugal
Degree Level
PhD
Field of study
Computer Science
Funding
PhD research studentship with a monthly stipend of €1,359.64 for 9 months, renewable up to 3 years. The post is funded by a La Caixa Foundation-funded project and includes personal accident insurance and optional social insurance.
Deadline
Expired
Country
Portugal
University
University of Porto

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Ongoing programLa Caixa Foundation
by la Caixa Foundation
la Caixa Foundation supports competitive doctoral fellowships and research funding, notably the INPhINIT programme for early-stage researchers pursuing PhD training in Spain and Portugal.
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About this position
PhD research studentship available in computational drug discovery for Machado-Joseph disease at the University of Porto, Faculty of Medicine (FMUP). The project is part of a La Caixa Foundation-funded initiative and is supervised by Sérgio Filipe Sousa (Group Leader, BioSIM – Biomolecular Simulations Group; Assistant Professor, University of Coimbra).
The research focuses on targeted protein degradation strategies for the mutant ATXN3 protein, combining molecular dynamics simulations, virtual screening, docking, free energy calculations, and AI-based molecular design. The work is highly relevant to chemistry, computational biology, bioinformatics, medicinal chemistry, and disease-oriented medical science.
Funding includes a monthly stipend of €1,359.64, initially for 9 months and renewable for up to 3 years. The position also includes personal accident insurance and optional social insurance.
Eligibility highlights: applicants should have a master's degree in Chemistry, Biochemistry, Chemical Engineering, Bioinformatics, Computational Biology, Medicinal Chemistry, or a related field, and must be enrolled in a doctoral program. Preferred experience includes molecular dynamics, docking, virtual screening, AI methods in molecular design, programming skills, and a master's average of at least 16/20.
Application deadline: 2026-05-12. Apply via the University of Porto portal using reference BOLS-ICBAS-26-2. Required documents include a CV, motivation letter, academic certificates, and proof of doctoral enrollment.
Funding details
PhD research studentship with a monthly stipend of €1,359.64 for 9 months, renewable up to 3 years. The post is funded by a La Caixa Foundation-funded project and includes personal accident insurance and optional social insurance.
What's required
Applicants must hold a master's degree in Chemistry, Biochemistry, Chemical Engineering, Bioinformatics, Computational Biology, Medicinal Chemistry, or a related field, and must be enrolled in a doctoral program. Preferred qualifications include a master's grade average of at least 16/20, experience with molecular dynamics, docking, and virtual screening, knowledge of AI methods in molecular design, and programming skills.
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