A PhD position is available in the lab of Professor Katja Petzold at Uppsala University, Sweden. The research focuses on understanding RNA and its regulation through structural changes, combining interests in RNA biology, biochemistry, and molecular biology. Uppsala University is recognized as one of the top 100 universities globally and offers a stimulating and supportive research environment. The position is ideal for candidates passionate about RNA structure and regulation, and who wish to contribute to cutting-edge research in medical biochemistry. Applicants are expected to have a relevant background in biochemistry, molecular biology, or related fields. For more information and to apply, follow the provided application link.

Uppsala University is offering one PhD and one postdoctoral position in the field of RNA structural biology, dynamics, and biophysics, with a focus on understanding RNA regulation in living cells. The research is based at the Department of Medical Biochemistry and Microbiology (IMBIM) and the Excellence Centre for the Chemical Mechanisms of Life, providing a vibrant international environment for interdisciplinary research and education. The PhD project, supervised by Professor Katja Petzold, centers on the structural dynamics and regulation of RNA in cellular contexts. The research group investigates how RNA molecules adopt multiple conformational states and how these transitions are regulated within cells, impacting gene expression. The project employs advanced techniques such as RNA structural probing (SHAPE-MaP, DMS-MaP, RABS), NMR spectroscopy (including in-cell and solution NMR), computational modeling, and various biophysical and biochemical methods to study RNA-protein and RNA-ligand interactions. Functional analyses span diverse biological systems, including microRNAs, ribosomal RNA elements, and viral RNA motifs. The postdoctoral position is part of the Excellence Centre for the Chemical Mechanisms of Life, a multidisciplinary initiative funded by the Swedish Research Council. The postdoc will work within the Petzold group and collaborate with other research leaders, focusing on RNA biophysics and structure under biologically relevant conditions. The role involves high-level research, method development, and active participation in the center's collaborative projects, including seminars and interdisciplinary activities. Applicants for the PhD position should hold a master's degree in chemistry, biochemistry, molecular biology, biophysics, structural biology, or a related field, with a strong focus on RNA. Laboratory experience with biomolecules or RNA molecular biology is required, along with excellent English skills, independence, creativity, and teamwork. Programming, advanced data analysis, and experience with NGS, structural biology, or biophysical methods are advantageous. The postdoc position requires a PhD in natural or technical sciences, with expertise in RNA biophysics, biochemistry, and/or NMR. Additional merits include RNA sample preparation, cell handling, data/statistics/programming, pathway analysis, and scientific writing. IELTS/TOEFL results are desirable but not mandatory. Both positions are fully funded, with the PhD appointment offering a full-time, fixed-term contract and salary according to local agreements, and the postdoc position providing a two-year, full-time contract with individual salary setting. Employment includes social benefits and access to university resources. To apply, candidates should submit their application via the Uppsala University recruitment system, including a CV, cover letter, degree certificates, transcripts, a scientific/technical text, publications, and contact details for two referees. PhD applicants should also include reflections on the use of AI/LLM in research. The application deadlines are February 20, 2026, for the PhD position and February 23, 2026, for the postdoc position. For further information, contact Professor Katja Petzold at [email protected]. Uppsala University is recognized for its strong international standing and commitment to high-quality research and education.

Uppsala University is offering a PhD position in Cellular RNA Structural Biology and Biophysics at the Department of Medical Biochemistry and Microbiology (IMBIM). The research focuses on the structure, dynamics, and function of RNA molecules in cells, with strong links to structural biology and molecular biophysics. The project, led by Professor Katja Petzold, aims to understand how RNA structures change in cells, what triggers these transitions, and the molecular mechanisms by which RNA dynamics regulate gene expression. The doctoral student will use advanced techniques such as RNA structural probing (SHAPE-MaP, DMS-MaP, RABS), NMR spectroscopy (including in-cell and solution NMR), computational modeling, and various biophysical and biochemical methods to study RNA-protein and RNA-ligand interactions. Functional analyses will be performed in different cellular systems, including viruses, bacteria, and human cells. The research environment is highly international and collaborative, with opportunities to work on regulatory microRNAs, ribosomal RNA elements, or viral RNA motifs depending on the candidate's interests and expertise. Applicants must hold an advanced degree in chemistry, biochemistry, molecular biology, biophysics, structural biology, or a related field, with a focus on RNA. Laboratory experience with biomolecules, nucleic acid biochemistry, or RNA molecular biology is required. Additional merits include programming/data analysis skills, experience with NGS data, structural biology or biophysical methods, and a strong interest in RNA structure and quantitative modeling. Excellent English communication skills, creativity, and the ability to work independently and collaboratively are essential. The position is a full-time, fixed-term doctoral employment with salary according to local agreements. The application deadline is 20 February 2026. Applications must be submitted via the Uppsala University recruitment system and include a CV, personal statement, reflections on AI/LLM in research, thesis or scientific text, publications, transcripts, and contact details for two referees. For more information, contact Professor Katja Petzold at [email protected].