Extending Small Molecule Orbitrap Isotope Ratio Mass Spectrometry Capabilities for Environmental Science and Geochemistry University of Glasgow in United Kingdom

This PhD project at the University of Glasgow’s Scottish Universities Environmental Research Centre (SUERC) offers an exciting opportunity to advance analytical methods for measuring isotope distributions in small molecules, with a primary focus on methane. The research aims to develop new capabilities for Orbitrap mass spectrometry, enabling precise measurement of isotopologues below mass 40 and expanding the range of applications in geochemistry and environmental science.

Methane, a critical greenhouse gas and a key component in natural gas and microbial metabolism, is central to this project. Isotope measurements, particularly clumped isotope analysis, have revolutionized our understanding of methane’s behavior in the environment. Traditional methods require large sample sizes and lengthy measurement times, but SUERC’s high-resolution Orbitrap mass spectrometer offers significant advantages in sample requirements, isotopologue coverage, and versatility. The project will involve cross-validation with established magnetic sector mass spectrometry methods and the development of standardization and optimization protocols for environmental applications.

The successful candidate will contribute to analytical development, including laboratory standards production, sample purification using cryogenic and gas chromatography techniques, and improvements in sample introduction systems. The research will provide new tools for studying small molecules in geochemistry, climate science, and other fields of economic and scientific importance.

Applicants should have a background in chemistry, engineering, quantitative geoscience, environmental sciences, or physics. Experience with mass spectrometry, laboratory vacuum techniques, gas chromatography, or scientific programming is valued. The candidate will receive training in advanced mass spectrometry techniques, stable and clumped isotope theory, methane geochemistry, and analytical development from a multidisciplinary supervisory team.

The project includes opportunities for extended placements at Thermo Fisher Scientific’s Research and Development hub in Bremen, Germany, offering hands-on experience in instrument design and prototyping. The PhD is part of a mini-CDT cohort of six students, fostering collaboration across complementary projects and advancing novel approaches in geochronology.

Full financial support is provided, covering tuition fees, a UKRI-aligned stipend for 42 months, and all laboratory and research travel costs. The position is open to applicants worldwide, with the anticipated start date in September 2026. The student will be based at SUERC in East Kilbride, near Glasgow.

To apply, visit the University of Glasgow College of Science and Engineering Graduate School application portal. Clearly state the project title, list the primary SUERC supervisor, and select SUERC as the host department. For further information, contact Dr Matthieu Clog at [email protected].