Publisher
source

Coventry University

Funded PhD in class B GPCR structure and function for drug discovery at Coventry University Coventry University in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Funded PhD project supported by UKRI via the BBSRC Doctoral Landscape Awards through the Midlands Integrative Biosciences Training Partnership. Funding notes mention tuition fees and stipend.

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Country

United Kingdom

University

Coventry University

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Keywords

Cell Biology
Molecular Biology
Biology
Medical Science
Signaling Pathway
G Protein-coupled Receptor

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About this position

Coventry University’s Centre for Discoveries in Life Sciences is advertising a funded PhD project within the Midlands Integrative Biosciences Training Partnership (MIBTP), a BBSRC Doctoral Training Partnership supported by UKRI. The project is titled Decoding class B G-protein-coupled receptor structure and function for drug and focuses on G-protein-coupled receptors (GPCRs), calcitonin receptor-like receptor (CLR), RAMPs, receptor folding and trafficking, cell-surface expression, and signalling pathways relevant to migraine, cardiovascular regulation, lymphatic development, fertility, and drug discovery.

The research will investigate how structural changes in the receptor extracellular region, especially ECL1, affect CLR function. The lab has generated single, double, and triple amino-acid deletion mutants across ECL1 to test how loop shortening and amino-acid composition influence receptor folding, trafficking, plasma membrane interactions, and signalling. This is a strong fit for students interested in cell biology, biological sciences, physiology, and human genetics-related receptor biology.

The opportunity is based in Coventry, United Kingdom. The post states that students from a wide diversity of academic backgrounds are encouraged to apply. Entry criteria include a minimum 2:1 first degree in a relevant subject, at least 60% in the project element or equivalent, and a minimum 60% overall module average. International applicants must meet English language requirements, typically IELTS Academic 7.0 overall with 6.5 in each section or TOEFL iBT 95 overall with 21 in each section.

Funding notes mention tuition fees and stipend. The project is part of the MIBTP PhD cohort funding, with cohorts starting in October 2025. To apply, candidates should first check eligibility, complete the ED&I form (which also serves as an expression of interest), and then complete the application form. Administrative questions can be directed to [email protected].

Funding details

Funded PhD project supported by UKRI via the BBSRC Doctoral Landscape Awards through the Midlands Integrative Biosciences Training Partnership. Funding notes mention tuition fees and stipend.

What's required

Applicants should have a minimum 2:1 first degree in a relevant discipline, with at least 60% in the project element or equivalent and a minimum 60% overall module average. Non-native English speakers must demonstrate English proficiency, typically IELTS Academic 7.0 overall with at least 6.5 in each component or TOEFL iBT 95 overall with at least 21 in each component. The call says students from a wide diversity of academic backgrounds are encouraged to apply.

How to apply

Check your eligibility, complete the ED&I form as an expression of interest, then complete the application form. Review the MIBTP Data Privacy Policy and contact [email protected] for administrative questions.

More information can be found here

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