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Medical Research Council (Cambridge)

PhD in Cell Biology, Developmental Biology, and Molecular Biology: How the embryo gets its shape Medical Research Council (Cambridge) Laboratory of Molecular Biology in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Competition funded PhD project.

Deadline

Dec 8, 2026

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Country

United Kingdom

University

Medical Research Council (Cambridge)

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Keywords

Cell Biology
Molecular Biology
Biology
Developmental Biology
Medical Science
Mechanobiology
Organogenesis

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About this position

PhD opportunity: How the embryo gets its shape at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with Dr K McDole.

This project focuses on cell biology, developmental biology, and molecular biology, asking how complex 3D structures arise from initially homogeneous cell populations during early mammalian development. The lab studies how tissues fold, tubes involute, organs form, and how physical forces and changing mechanical environments influence cell behavior, gene expression, and fate.

The McDole lab uses advanced adaptive light-sheet microscopy together with specialized experimental tools and computational methods to visualize embryo development in real time and reconstruct early mammalian development quantitatively. The project aims to uncover the mechanisms shaping tissues and organs, with examples including the coordinated organization of the embryo’s anterior side, such as the heart, brain, and early gut.

This is a competition funded PhD project and is open to students worldwide. The listing is hosted by FindAPhD and invites interested applicants to register their interest online. The university will respond directly to enquiries.

Application window / deadline: Tuesday, 8 December 2026.

Useful links: references are provided in the post, including PubMed and bioRxiv links, and the application/enquiry page is on FindAPhD.

Funding details

Competition funded PhD project.

What's required

Applicants should be interested in developmental biology, cell biology, and molecular biology. The project is suitable for students worldwide and involves advanced light-sheet microscopy and computational analysis; prior experience in microscopy, quantitative biology, or related experimental/computational methods would be helpful if available.

How to apply

Register your interest through the FindAPhD enquiry form. The university will respond directly to applicants by email.

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Review drafts and confirm requirements with the university.