Funded PhD in GPCR Signalling, Proteostasis, and Neuropsychiatric Genetics University of Bristol in United Kingdom

Department of Pathology, University of Cambridge is advertising a fully funded PhD studentship in the lab of Professor Heike Laman . The project investigates how ubiquitin regulates secretory trafficking in dopaminergic neurons , with a focus on how the E3 ubiquitin ligase subunit FBXO7 controls protein movement through the secretory pathway. The research uses human stem cell-derived neurons as a model system and combines live-cell imaging , RUSH assays , proteomics , and functional experiments....

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences on PINK1 , mitochondrial quality control , and Parkinson’s disease . The project, supervised by Prof I Collinson and Dr Robin Corey , investigates how PINK1 switches between alternative fates in mitochondria: matrix import versus cleavage/retro-translocation and outer-membrane activation. The research combines biochemistry , biophysics , cell biology , and computational modelling to study the co...

Postdoctoral Research Scientist in Redox and Phosphatase Biochemistry at the Babraham Institute, London, United Kingdom. This postdoctoral opportunity sits in an ambitious research programme studying how reactive oxygen species (ROS) regulate protein tyrosine phosphatases (PTPs) and shape cell signalling. The project explores redox regulation as a fundamental mechanism in signal transduction, with a focus on phosphatase oxidation, recovery, substrate selection, and signalling specificity. The su...

Postdoctoral Associate at Duke University School of Medicine in the Boyce Laboratory (Department of Biochemistry), Durham, North Carolina, United States. This postdoctoral opening is part of a newly funded NINDS R01 project studying how O-GlcNAc glycosylation regulates KLHL-family E3 ubiquitin ligases (including gigaxonin and KLHL3) and their substrates (neurofilaments and WNK kinases) in neuronal proteostasis , cytoskeletal dynamics , and ferroptotic cell death . The work combines biochemistry ...

Jessica Cross is sharing a funded research associate/postdoc opportunity in the University of Bristol lab focused on protein design , protein engineering , and intracellular transport . The role is described as a 3-year funded position and appears to be a research associate/senior research associate appointment. The project aims to use protein design and engineering to manipulate intracellular transport, making it a strong fit for candidates with interests in cell biology, molecular design, and ...