The Francis Crick Institute
1 week ago
Funded PhD in maternal immune evolution, placenta biology, and single-cell genomics The Francis Crick Institute in United Kingdom
Degree Level
PhD
Field of study
Computer Science
Funding
Funded PhD project. Successful applicants will receive a non-taxable annual stipend of £27,715 plus payment of university tuition fees.
Deadline
Nov 2, 2026
Country
United Kingdom
University
The Francis Crick Institute

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About this position
Funded PhD project at The Francis Crick Institute with Dr Margarida Cardoso Moreira in London, United Kingdom.
This project asks how maternal immune systems evolved to support the placenta and tolerate genetically mismatched embryonic tissue. The research combines developmental biology, evolution, genomics, immunology, reproductive biology, and bioinformatics, with a strong emphasis on analysing large single-cell datasets. A key comparative angle is the study of pregnancy in mammals and in a fish family (Poeciliidae) that has evolved placentas independently multiple times. The goal is to map reproductive immune systems across these systems and understand how immune tolerance to the placenta is built and diversified across evolution.
The project is especially suitable for applicants who enjoy computational biology and large-scale genomic data analysis. The posting explicitly notes that much of the work involves analysing large single-cell datasets, so prior interest in computational approaches is important. The lab also asks applicants to reflect on a scientific paper they have enjoyed and to think critically about the next question that paper leaves open.
Funding is provided: successful applicants will receive a non-taxable annual stipend of £27,715 plus full university tuition fees. Students of all nationalities are eligible to apply.
This is a PhD opening for a 2027 Crick PhD project. The deadline shown on the page is 2026-11-02.
Funding details
Funded PhD project. Successful applicants will receive a non-taxable annual stipend of £27,715 plus payment of university tuition fees.
What's required
Applicants should be excited to work computationally with large-scale genomic data. The project is suitable for candidates interested in analysing large single-cell datasets and exploring reproductive immunology, placenta evolution, developmental biology, genomics, and bioinformatics. Students of all nationalities are eligible to apply.
How to apply
Review the project details and prepare an application for the 2027 Crick PhD project with Dr Margarida Cardoso Moreira. Answer the lab-specific question about a scientific paper you enjoyed and the next question you would pursue. Submit through the FindAPhD/Crick application route linked from the posting.
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