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Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V.

PhD candidate in Biofluorescence, melanoma therapy resistance and tumor immunology Leibniz Institute for Analytical Sciences ISAS in Germany

Degree Level

PhD

Field of study

Immunotherapy

Funding

Part-time PhD position at 65% salary, funded by the DFG as part of CRC 1752. Contract runs until June 30, 2030. Salary follows German TV-L pay group 13.

Deadline

Expired

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Country

Germany

University

Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V.

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Keywords

Immunotherapy
Cancer Biology
Biology
Microscopy
Translational Medicine
Medical Science
Melanoma
Tumor Immunology
Neutrophil
Bioinformatic

About this position

PhD candidate opportunity in Biofluorescence at the Leibniz Institute for Analytical Sciences (ISAS) in Dortmund, Germany. The project is part of the DFG-funded CRC 1752 DYNAMO: Immediate Tumor Dynamics in Melanoma Therapy and focuses on understanding the role of neutrophils in the early development of therapy resistance in human melanoma.

The research combines tumor immunology, melanoma biology, immune checkpoint inhibitor response, few-cell proteomics, multicolor flow cytometry, live-cell imaging, advanced microscopy, and data analysis in collaboration with computational partners. The project is carried out with the University Hospital Essen and the University of Duisburg-Essen.

Applicants should have a completed diploma or master’s degree in molecular biology, cancer biology, immunology, cell biology, bioinformatics, translational medicine, or a related field. Experience with molecular/cellular biology and functional immune cell assays is preferred; experience with neutrophils or myeloid cells is an advantage. Strong interest in translational cancer research, tumor–immune interactions, and melanoma is important. English fluency is required.

The position is part-time (65%), starts on 2026-10-01, and is funded according to the German TV-L EG 13 scale. The contract runs until 2030-06-30. ISAS offers training, international research exposure, access to state-of-the-art platforms, flexible working, social benefits, and support for accommodation/administrative matters for non-residents.

Application deadline: 2026-08-14. Apply through the applicant portal and use reference number 411_2026. Questions can be sent to [email protected].

Funding details

Part-time PhD position at 65% salary, funded by the DFG as part of CRC 1752. Contract runs until June 30, 2030. Salary follows German TV-L pay group 13.

What's required

Completed diploma or master’s degree in molecular biology, cancer biology, immunology, cell biology, bioinformatics, translational medicine or a related discipline. Experience in molecular and cellular biology techniques is expected, with hands-on functional immune cell assays preferred; experience with neutrophils or myeloid cells is an advantage. Strong interest in melanoma biology, tumor immunology, immune checkpoint therapy, translational cancer research, and tumor-immune interactions is required. Experience with cell culture, flow cytometry, microscopy, proteomics workflows, or high-dimensional immune profiling is desirable. Bioinformatics or biostatistics experience is beneficial but not required. Applicants should work independently and in interdisciplinary teams, have strong organizational and analytical skills, be self-motivated, curious, reliable, creative, team-oriented, and fluent in spoken and written English.

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