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Institut de Biologie Structurale

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PhD in Biochemistry: CB1R Signaling, Crip1a, PUFAs, NMR and Modelling Centre de biologie structurale in France

Degree Level

PhD

Field of study

Pharmacology

Funding

Full funding available

Deadline

Aug 21, 2026

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Country

France

University

Institut de Biologie Structurale

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Keywords

Pharmacology
Biochemistry
Chemistry
Biology
Structural Biology
Medical Science
Nmr Spectroscopy
Allosteric Regulation
Physics

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About this position

Applications are invited for a full-time PhD position (36 months) at the Centre de Biologie Structurale (CBS), Montpellier, France, within CNRS.

The project is in biochemistry and structural biology, focusing on how Crip1a and PUFAs shape the signaling of the CB1R GPCR. The research aims to understand long-range allosteric interactions, lipid-dependent modulation, receptor conformational landscapes, and selectivity toward specific Gαi protein subtypes.

The work will use advanced NMR methods, integrative modelling, protein purification, specific labelling with non-natural amino acids, and structural/dynamic analysis at atomic resolution. The project is described as contributing to the rational design of selective compounds of pharmacological interest.

Eligibility highlights: Bachelor degree or equivalent; basic French; no prior research experience required. The post is listed as a temporary, full-time doctoral contract.

Funding: The PhD is funded by ANR for 36 months. The announcement notes it is not funded by an EU research framework programme.

Deadline: 21 August 2026, 23:59 UTC.

How to apply: Use the CNRS application page linked in the post. A Euraxess view/apply link is also provided for reference.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

How to apply

Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.

More information can be found here

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