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German Cancer Research Center

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PhD in Cancer Genomics, DNA Break Mapping and Multi-omics at German Cancer Research Center (DKFZ) German Cancer Research Center in United Kingdom

Degree Level

PhD

Field of study

Computer Science

Funding

Full funding available

Deadline

Jul 30, 2026

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Country

United Kingdom

University

German Cancer Research Center

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Keywords

Computer Science
Biomedical Engineering
Biology
Mathematics
Computational Biology
Cancer Research
Medical Science
Oncogenomics
Genomic Instability
Omics
Statistics
Bioinformatic

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About this position

PhD opening at the German Cancer Research Center (DKFZ) in Heidelberg, Germany, in the Junior Research Group Brain Mosaicism and Tumorigenesis headed by Dr. Pei-Chi Wei.

The project sits at the intersection of cancer biology, bioinformatics, genomics, statistics, and medical science. The lab studies how replication stress, transcription–replication conflicts, and DNA repair pathways shape DNA double-strand breaks, copy-number alterations, and genome instability. The PhD work will focus on mapping replication-stress-mediated and naturally occurring DNA breaks at nucleotide resolution and integrating multi-omics datasets, including DSB maps, replication timing/direction, transcription orientation, and R-loop profiles.

Research topics mentioned in the post include osteosarcoma, breast cancer, leukemia, neural progenitor cells, translational cancer research, and data analysis. The lab uses high-resolution genome biology methods such as LAM-HTGTS, Hi-RepliSeq, GRO-seq, and DRIP-seq, so this is a strong fit for candidates interested in experimental genomics and computational analysis.

Eligibility highlights: a master's degree in biology, bioinformatics, genetics, genomics, bioengineering, applied mathematics, or a related field; good university performance in biology for biology-trained applicants; intermediate R or Python skills and prior omics analysis experience are advantageous for computationally oriented applicants; strong English skills; self-motivation and ability to work independently and collaboratively.

Funding: fully funded doctoral salary with usual social benefits. Additional benefits include 30 days of vacation, flexible working hours, possible mobile/part-time work, subsidized Germany job ticket, and mentoring/training through DKFZ programs.

Application window: deadline is 30 July 2026. Applications are reviewed immediately and accepted until the position is filled. Apply via the official portal; CV, cover letter, transcripts, and two references are required. Email applications are not accepted.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

How to apply

Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.

More information can be found here

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