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PhD in preclinical outcomes in zebrafish models of leukodystrophies University of York in United Kingdom
Degree Level
PhD
Field of study
Computer Science
Funding
Marie Skłodowska-Curie Doctoral Network PhD position. The selected candidate will be employed by the University of York and join the POLARIS consortium; the post includes network training and planned secondments. No stipend amount is stated in the post.
Deadline
Oct 5, 2026
Country
United Kingdom
University
University of York
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About this position
MSCA-DN PhD opportunity in preclinical outcomes in zebrafish models of leukodystrophies within the POLARIS doctoral network.
The project is hosted by the University of York and focuses on accelerating therapy development for leukodystrophies, rare genetic disorders affecting brain white matter. The selected PhD candidate will work with Dr Noémie Hamilton at the York Biomedical Research Institute and the Department of Biology, with academic research and the PhD defence based at York.
Research topics include zebrafish disease models, preclinical outcome measures, behavioural assays, multimodal imaging, MRI, high-resolution confocal microscopy, electron microscopy, and imaging analysis pipelines. The project compares outcomes across models of RNASET2 deficiency, adrenoleukodystrophy (ALD), Krabbe disease, and metachromatic leukodystrophy (MLD), aiming to identify robust and reproducible readouts relevant to preclinical therapy development.
The POLARIS network offers an international and interdisciplinary training environment, including planned secondments at Zantiks and the University of Liverpool’s Centre for Preclinical Imaging. These placements provide exposure to behavioural analysis technology, commercial translation, and advanced imaging platforms such as MRI, PET, CT, SPECT, ultrasound, photoacoustic imaging, MPI, optical imaging, and hyperthermia.
This is a PhD opening under a European doctoral network. The post is research-focused and does not mention a scholarship programme name beyond MSCA-DN/POLARIS. No specific stipend amount is stated in the post.
Deadline: 2026-10-05.
How to apply: Use the AcademicTransfer link in the post to open the vacancy page and submit your application through the portal. Review the full job description and eligibility details before applying.
Funding details
Marie Skłodowska-Curie Doctoral Network PhD position. The selected candidate will be employed by the University of York and join the POLARIS consortium; the post includes network training and planned secondments. No stipend amount is stated in the post.
What's required
Applicants should be suitable for a PhD-level doctoral training position and interested in zebrafish disease models, leukodystrophies, preclinical imaging, behavioural assays, and quantitative analysis. The project particularly suits candidates with experience or strong interest in biology, biomedical imaging, experimental model systems, and data analysis. The post is part of the POLARIS Doctoral Network and includes international training and secondments.
How to apply
Apply via the AcademicTransfer application page linked in the post. Review the full vacancy details and submit the application through the portal before the deadline. The academic research and PhD defence will be based at the University of York.
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