University of Edinburgh
Top university
1 week ago
PhD in Stress-Responsive RNA-Protein Interactions and Isoform Regulation in Cardiomyocytes University of Edinburgh in United Kingdom
Degree Level
PhD
Field of study
Cell Biology
Funding
Competition-funded 4-year PhD studentship through the EASTBIO BBSRC Doctoral Training Partnership. Funding covers a stipend and UK-level tuition fees; the University of Edinburgh covers the difference between home and international fees, so the studentship is fully funded for appointees. There is a cap on the number of international students recruited.
Deadline
Nov 16, 2026
Country
United Kingdom
University
University of Edinburgh
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.
Apply for this position
Keywords
Suggested positions
About this position
PhD opportunity at the University of Edinburgh in stress-responsive RNA-protein interactions and isoform regulation in cardiomyocytes.
This EASTBIO-funded project sits in the School of Neurological and Cardiovascular Sciences (College of Medicine and Veterinary Medicine) and is supervised by Dr Appie Beqqali and Dr Sander Granneman. The research asks how cardiomyocytes reorganise their RNA-bound proteome during stress and recovery, and whether different stresses produce shared or stress-specific changes in RNA-binding activity that reshape transcript isoforms.
The project combines cell biology, molecular biology, cardiology, proteomics, short-read and long-read RNA sequencing, bioinformatics, and direct RNA-binding/perturbation assays. Planned work includes hypoxia-reoxygenation, oxidative stress, proteotoxic/endoplasmic-reticulum stress, OOPS, quantitative mass spectrometry, differential splicing analysis, long-read transcript structure resolution, and validation in human 3D cardiac tissue where feasible.
Funding: 4-year competition-funded PhD studentship via the EASTBIO BBSRC Doctoral Training Partnership. The award covers stipend and UK-level tuition fees; the University of Edinburgh covers the difference between home and international fees, making it fully funded for appointees. International applicants are welcome, subject to EASTBIO/UKRI eligibility and the international student cap.
Eligibility/requirements: Applicants should have a strong relevant degree and meet EASTBIO/UKRI criteria. A background or interest in RNA biology, cardiomyocyte models, proteomics, sequencing, and quantitative analysis would be helpful.
How to apply: Download and complete the EASTBIO Application Form and reference form guidance. Email the completed form plus academic transcripts (PDF) to [email protected]. Ask referees to submit references to the same email address by the deadline.
Deadline: 16 November 2026.
Funding details
Competition-funded 4-year PhD studentship through the EASTBIO BBSRC Doctoral Training Partnership. Funding covers a stipend and UK-level tuition fees; the University of Edinburgh covers the difference between home and international fees, so the studentship is fully funded for appointees. There is a cap on the number of international students recruited.
What's required
Applicants should have or expect a strong relevant undergraduate degree (the page references a BSc Honours project as preparation). The project is open to UK and international students and applicants must meet EASTBIO/UKRI eligibility criteria, including fee-status considerations for international applicants. Interest or background in RNA biology, cardiomyocyte or cell biology, proteomics, sequencing, bioinformatics, and reproducible quantitative analysis would be advantageous.
How to apply
Complete the EASTBIO Application Form and attach your academic transcripts as a PDF. Email the application and transcripts to [email protected], and ask your referees to send their references using the EASTBIO reference form template to the same email address by the deadline.
More information can be found here
Ask ApplyKite AI
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.