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Marius Lange

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PhD Position in Generative Modeling of Human Development and Disease University of Basel in Switzerland

Degree Level

PhD

Field of study

Computer Science

Funding

Fully funded four-year PhD position (100%) with generous resources for computation and data generation. Internationally competitive salary and social benefits according to University of Basel rules; enrolment in the International PhD Programme in Biomedicine with courses, skills training, and career development.

Deadline

Oct 16, 2026

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Country

Switzerland

University

University of Basel

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Keywords

Computer Science
Biomedical Engineering
Biology
Computational Biology
Regulation
Medical Science
Disease Biology
Cytoskeleton Dynamics
Generative Modeling
Human Development
Statistics
Bioinformatic
Continual Learning

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About this position

PhD opportunity at the University of Basel in the Computational Cellular Dynamics (CCD) Lab led by Marius Lange, based at the Department of Biomedicine and the Basel Research Centre for Child Health (BRCCH). The project focuses on generative modeling of human development and disease, with an emphasis on single-cell genomics, spatial genomics, sequencing, imaging, and computational biology.

The successful candidate will develop models for human developmental and disease biology, with possible directions including: cell-cell communication, joint models of regulation and dynamics, and intervention design and continual learning. The lab builds on prior work such as scVelo, CellRank, CellRank 2, moslin, moscot, and RegVelo, and collaborates with hospital and university partners in Basel to generate new data on modern spatial and single-cell platforms.

This is a fully funded 4-year PhD position (100%) with generous computational and data-generation resources, competitive salary and social benefits, and enrolment in the International PhD Programme in Biomedicine.

Eligibility highlights: MSc in computer science, mathematics, physics, engineering, computational biology, or a related quantitative field; hands-on experience with biological data; strong Python skills; experience with PyTorch or JAX; statistical grounding; fluent English; GitHub account with code. Experience with single-cell or spatial genomics and open-source scientific software is desirable.

Application deadline: 2026-10-16. Apply through the online portal and include a motivation letter, short research-project description, CV, GitHub link, MSc transcript, and contact details for at least two references.

Location: Basel, Switzerland.

Funding details

Fully funded four-year PhD position (100%) with generous resources for computation and data generation. Internationally competitive salary and social benefits according to University of Basel rules; enrolment in the International PhD Programme in Biomedicine with courses, skills training, and career development.

What's required

MSc in computer science, mathematics, physics, engineering, computational biology or a related quantitative field; hands-on experience with biological data; strong Python skills and experience with PyTorch or JAX; statistical grounding to reason about the models used; a GitHub account with code written by the applicant; fluent English. Desirable: experience with single-cell or spatial genomics data and contributions to open-source scientific software.

How to apply

Apply via the online platform. Upload a motivation letter, a short description of a research project, CV, GitHub link, MSc transcript, and contact details of at least two references. For questions, email Prof. Dr. Marius Lange.

More information can be found here

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