International PhD Programme (IPP) Mainz, Institute of Molecular Biology
Just Landed
New Today
PhD Position in Molecular Immunology: Modelling Myeloid Cell Activation and Exhaustion on a Single-Cell Scale International PhD Programme (IPP) Mainz, Institute of Molecular Biology in Germany
Degree Level
PhD
Field of study
Inflammation
Funding
Available
Deadline
Oct 15, 2026
Country
Germany
University
International PhD Programme (IPP) Mainz, Institute of Molecular Biology
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.
More information can be found here
Keywords
Suggested positions
About this position
The International PhD Programme (IPP) Mainz at the Institute of Molecular Biology in Germany is offering a fully funded PhD position in molecular immunology.
The project, supervised by Johannes Mayer, focuses on modelling myeloid cell activation and exhaustion on a single-cell scale. It investigates circulating myeloid cells such as monocytes, dendritic cells, granulocytes, and their bone marrow progenitors under inflammatory and non-inflammatory conditions. The research aims to understand how these cells reconfigure during local and systemic inflammation, and how cell-cell communication from stromal, endothelial, and lymphoid niches shapes differentiation and function.
The project combines single-cell and multi-omic profiling with trajectory inference and ligand-receptor/network modelling to build a perturbation landscape across myeloid cell types and progenitors. The work includes in silico modelling, in vitro validation, datamining, LLM-based studies, in vitro activation, CRISPR/Cas9 perturbation screening, and in vivo inflammatory models spanning systemic and local inflammation.
This PhD is well suited to candidates with a strong immunology background and experience spanning both wet-lab and dry-lab research at single-cell resolution. A willingness to work with animal models is essential, including experimental handling, design, tissue processing, and analysis. Applicants must hold a Master’s degree or equivalent, have a good command of English, and provide two letters of reference.
The programme describes itself as an exciting, interdisciplinary, and international environment with advanced training in scientific techniques and professional skills, access to state-of-the-art core facilities, and a lively community of more than 200 PhD students from 44 countries. The position is fully funded and the financing continues until completion of the thesis.
The application deadline is 15 October 2026. Interviews are scheduled at IMB in Mainz on 18–19 January 2027, and the intended start date is between 1 February and 31 July 2027. Applicants should choose the project preference “Mayer (Activate)” in the IPP application platform and apply through the programme website.
Funding details
Available
What's required
Master or equivalent in a relevant biological sciences field is required. The candidate should have a strong background in immunology, previous experience with both wet lab and dry lab work at the single-cell level, and willingness to work with in vivo animal models, including handling, experimental design, tissue processing, and analysis. Good command of English is required, and 2 letters of reference are requested.
How to apply
Select 'Mayer (Activate)' as the project preference in the IPP application platform. Submit the application via the online form at the programme website and provide the required reference letters.
Ask ApplyKite AI
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.