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Radboud University

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PhD Position in Multisynaptic Plasticity in Dendrites Radboud University in Netherlands

Degree Level

PhD

Field of study

Psychology

Funding

Paid PhD employment at Radboud University with a temporary contract: 0.8 FTE for 5 years or 1.0 FTE for 4 years, initially 1.5 years with extension after positive evaluation. Starting gross monthly salary is €3,204, rising to €4,051 from the fourth year onwards, plus 8% holiday allowance, 8.3% end-of-year bonus, and extra leave days.

Deadline

Nov 8, 2026

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Country

Netherlands

University

Radboud University

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Keywords

Psychology
Biomedical Engineering
Biology
Neuropsychology
Medical Science
Synaptic Plasticity
Calcium Signaling
Biosensor

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About this position

PhD position in Multisynaptic Plasticity in Dendrites at Radboud University (Faculty of Science, Donders Centre for Neuroscience, Nijmegen, Netherlands).

This PhD project studies neuroscience, especially synaptic plasticity, dendrites, hippocampal CA1 neurons, intracellular signalling, calcium signalling, and the interaction of molecular pathways during simultaneous activation of multiple synapses. The work combines two-photon glutamate uncaging, advanced microscopy, single-cell electrophysiology, and novel biosensors to investigate how plasticity is coordinated within dendrites and how neuromodulators affect these processes.

The project is embedded in the Wierenga lab, which focuses on inhibitory synapses and their interactions with excitatory synapses. Research objectives include determining how calcium release from internal stores contributes to dendritic calcium signals, how PKA and PKC interact with calcium signals, whether these interactions explain two modes of spine growth, and when/where retrograde messengers are produced.

Eligibility highlights: applicants should have a Master's degree in neuroscience, life sciences, biology, biomedical sciences, or a related discipline; interest in optical recording methods and intracellular signalling; experience with microscopy and/or patch-clamp electrophysiology in living brain tissue is preferred; programming skills in Matlab/Python are a plus; fluent English is required.

Funding and conditions: this is a paid PhD employment with a temporary contract (0.8 FTE for 5 years or 1.0 FTE for 4 years), initially 1.5 years with extension after positive evaluation. Salary starts at €3,204 gross/month and rises to €4,051 from year four, plus holiday allowance, end-of-year bonus, and extra leave days.

Application deadline: 8 November 2026. Apply via the online application button and address the letter to Corette Wierenga.

Funding details

Paid PhD employment at Radboud University with a temporary contract: 0.8 FTE for 5 years or 1.0 FTE for 4 years, initially 1.5 years with extension after positive evaluation. Starting gross monthly salary is €3,204, rising to €4,051 from the fourth year onwards, plus 8% holiday allowance, 8.3% end-of-year bonus, and extra leave days.

What's required

Master's degree in neuroscience-related field, life sciences, biology, biomedical sciences or a related discipline. Interest in intracellular signalling and optical recording methods. Experience in advanced microscopy and/or single-cell patch-clamp electrophysiology in living brain tissue is preferred. Ability to program in Matlab, Python or a similar environment is ideal but not required. Fluent English and good communication skills, with a motivated, critical, creative, team-oriented, independent, and eager-to-learn profile.

How to apply

Apply only via the application button on the vacancy page. Address your letter of application to Corette Wierenga and include the documents requested in the application form. Submit before 8 November 2026.

More information can be found here

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